Journal
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
Volume 2015, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2015/578107
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Funding
- Shanghai Municipal Health and Family Planning Commission [ZY3-JSFC-2-2010, 20134090, ZYXK2012010]
- Pudong New Area Science and Technology Commission [PKJ2013-Y22]
- Pudong New Area Health and Family Planning Commission [PWZz2013-02, PWRd2013-03]
- State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources
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Rhein (4, 5-dihydroxyanthraquinone-2-carboxylic acid) is a lipophilic anthraquinone extensively found in medicinal herbs, such as Rheum palmatum L., Cassia tora L., Polygonum multiflorum Thunb., and Aloe barbadensis Miller, which have been used medicinally in China for more than 1,000 years. Its biological activities related to human health are being explored actively. Emerging evidence suggests that rhein has many pharmacological effects, including hepatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities. The present review provides a comprehensive summary and analysis of the pharmacological properties of rhein, supporting the potential uses of rhein as a medicinal agent.
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