Journal
JOURNAL OF ORTHOPAEDIC TRANSLATION
Volume 9, Issue -, Pages 69-75Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jot.2017.03.007
Keywords
stem cells; tendinopathy; tendon repair
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Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article, we attempt to provide a brief overview on the recent progress in the field, current understanding of the underlying mechanisms of the approach, and the potential of stem cell-based therapies beyond cell implantation. We conclude the review by sharing our viewpoints on the challenges, opportunities, and future directions of this approach. The translational potential of this article: This paper reviews recent progress on stem cell-based therapeutic approaches for tendon repair, which highlights its translational potential and challenges. (C) 2017 The Authors. Published by Elsevier (Singapore) Pte Ltd on behalf of Chinese Speaking Orthopaedic Society.
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