Journal
IMMUNE NETWORK
Volume 17, Issue 1, Pages 13-19Publisher
KOREA ASSOC IMMUNOLOGISTS
DOI: 10.4110/in.2017.17.1.13
Keywords
Vitamin; IgA; Inflammation; Regulatory T cell; Energy metabolism
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Funding
- MEXT/JSPS KAKENHI [16H01373, 15H05790, 26293111]
- Ministry of Health, Labour and Welfare (MHLW)
- Research on Development of New Drugs, the Japan Agency for Medical Research and Development (AMED)
- Science and Technology Research Promotion Program for Agriculture, Forestry, Fisheries, and Food Industry
- Astellas Foundation for Research on Metabolic Disorders
- Terumo Foundation for Life Sciences and Arts
- Suzuken Memorial Foundation
- Grants-in-Aid for Scientific Research [16H01373, 26293111, 15H05790] Funding Source: KAKEN
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Vitamins are micronutrients which are essential for the maintenance of biological responses including immune system. Hence, vitamin deficiency increases a risk of infectious, allergic, and inflammatory diseases. Accumulating evidence has recently revealed the molecular and cellular mechanisms of vitamin-mediated regulation in the active and quiescent immune responses. In this review, we focus on the immunologic roles of vitamins in the regulation of homeostasis and surveillance in the gut.
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