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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
The morphological and molecular features of the epithelial-to-mesenchymal transition
Gema Moreno-Bueno et al.
NATURE PROTOCOLS (2009)
Lactate promotes glioma migration by TGF-β2-dependent regulation of matrix metalloproteinase-2
Fusun Baumann et al.
NEURO-ONCOLOGY (2009)
Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
Elaine R. Mardis et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Lactate Dehydrogenase 5 Expression in Squamous Cell Head and Neck Cancer Relates to Prognosis following Radical or Postoperative Radiotherapy
Michael I. Koukourakis et al.
ONCOLOGY (2009)
Specific glycosphingolipids mediate epithelial-to-mesenchymal transition of human and mouse epithelial cell lines
Feng Guan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
SDH5, a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma
Huai-Xiang Hao et al.
SCIENCE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma
M. R. Morris et al.
BRITISH JOURNAL OF CANCER (2008)
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases
Monica Zerilli et al.
CANCER (2008)
An acidic extracellular pH induces Src kinase-dependent loss of β-catenin from the adherens junction
Kuo-Hsin Chen et al.
CANCER LETTERS (2008)
Hypoxia-inducible factor-1α regulates matrix metalloproteinase-1 activity in human bone marrow-derived mesenchymal stem cells
Jiunn-Liang Lin et al.
FEBS LETTERS (2008)
Metastasis is promoted by a bioenergetic switch: New targets for progressive renal cell cancer
Sigrun Langbein et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Pierre Sonveaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma
Raghothama Chaerkady et al.
JOURNAL OF PROTEOME RESEARCH (2008)
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
NATURE (2008)
Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma
Yasumasa Kato et al.
FEBS JOURNAL (2007)
Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231
Shannon M. Gallagher et al.
CANCER RESEARCH (2007)
Metabolic changes during carcinogenesis: Potential impact on invasiveness
Kieran Smallbone et al.
JOURNAL OF THEORETICAL BIOLOGY (2007)
Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
S. A. Hussain et al.
BRITISH JOURNAL OF CANCER (2007)
Expression of glucose transporter-1, hexokinase-II, proliferating cell nuclear antigen and survival of patients with pancreatic cancer
Andrej Lyshchik et al.
CANCER INVESTIGATION (2007)
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases
M. Krockenberger et al.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2007)
Glycolysis inhibition for anticancer treatment
H. Pelicano et al.
ONCOGENE (2006)
Succinate dehydrogenase and fumarate hydratase:: linking mitochondrial dysfunction and cancer
A. King et al.
ONCOGENE (2006)
Acid-mediated tumor invasion: a multidisciplinary study
RA Gatenby et al.
CANCER RESEARCH (2006)
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
S Langbein et al.
BRITISH JOURNAL OF CANCER (2006)
Transforming growth factor-beta: A molecular target for the future therapy of glioblastoma
W Wick et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Mitochondrial tumour suppressors: A genetic and biochemical update
E Gottlieb et al.
NATURE REVIEWS CANCER (2005)
Regulation of phosphoglucose isomerase/autocrine motility factor expression by hypoxia
T Funasaka et al.
FASEB JOURNAL (2005)
Negative regulation of the expressions of cytokeratins 8 and 19 by SLUG repressor protein in human breast cells
MK Tripathi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
TGF β1 induces prolonged mitochondrial ROS generation through decreased complex IV activity with senescent arrest in Mv1Lu cells
YS Yoon et al.
ONCOGENE (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-β-induced cell responses
CY Xin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Novel mechanism of tumorigenesis:: Increased transforming growth factor-β1 suppresses the expression of connexin 43 in BALB/cJ mice after implantation of poly-L-lactic acid
S Ahmed et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2004)
Lactate: Mirror and motor of tumor malignancy
S Walenta et al.
SEMINARS IN RADIATION ONCOLOGY (2004)
Fibronectin-induced COX-2 mediates MMP-2 expression and invasiveness of rhabdomyosarcoma
H Ito et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Hypoxia enhances the expression the motility of human pancreatic of autocrine motility factor and cancer cells
H Niizeki et al.
BRITISH JOURNAL OF CANCER (2002)
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
IPM Tomlinson et al.
NATURE GENETICS (2002)
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
DM Brizel et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)
Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells
Q Shi et al.
ONCOGENE (2001)
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
BE Baysal et al.
SCIENCE (2000)