4.6 Review

The Landscape of mtDNA Modifications in Cancer: A Tale of Two Cities

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

The Origin of Mitochondrial Cristae from Alphaproteobacteria

Sergio A. Munoz-Gomez et al.

MOLECULAR BIOLOGY AND EVOLUTION (2017)

Article Multidisciplinary Sciences

A molecular portrait of microsatellite instability across multiple cancers

Isidro Cortes-Ciriano et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection

Satish Srinivasan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2017)

Review Biochemistry & Molecular Biology

MtDNA As a Cancer Marker: A Finally Closed Chapter?

Elmar Kirches

CURRENT GENOMICS (2017)

Article Oncology

Molecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy

M. Cecilia Caino et al.

CLINICAL CANCER RESEARCH (2016)

Review Biochemistry & Molecular Biology

Mitochondria and the hallmarks of cancer

Evangelos Giampazolias et al.

FEBS JOURNAL (2016)

Article Cell Biology

Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression

Julie V. Philley et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2016)

Review Biochemistry & Molecular Biology

Mitochondria and Cancer

Sejal Vyas et al.

Review Cell Biology

Regulators of mitochondrial dynamics in cancer

Daniela Senft et al.

CURRENT OPINION IN CELL BIOLOGY (2016)

Article Cell Biology

TP53 mutation, mitochondria and cancer

William M. Kamp et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2016)

Review Chemistry, Medicinal

The Role of Mitochondria in Cancer Induction, Progression and Changes in Metabolism

Malgorzata Rogalinska

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2016)

Review Biochemistry & Molecular Biology

Mitochondria and Cancer

Wei-Xing Zong et al.

MOLECULAR CELL (2016)

Article Biochemistry & Molecular Biology

HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing

Hansi Weissensteiner et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Medicine, Research & Experimental

Mitochondrial DNA heteroplasmy in human health and disease

George B. Stefano et al.

BIOMEDICAL REPORTS (2016)

Article Genetics & Heredity

Mitochondrial DNA Polymerase Mutations and Their Implications in mtDNA Alterations in Colorectal Cancer

Katarzyna Linkowska et al.

ANNALS OF HUMAN GENETICS (2015)

Article Genetics & Heredity

Heteroplasmic substitutions in the entire mitochondrial genomes of human colon cells detected by ultra-deep 454 sequencing

Katarzyna Skonieczna et al.

FORENSIC SCIENCE INTERNATIONAL-GENETICS (2015)

Article Genetics & Heredity

Mitochondrial DNA heteroplasmy in the emerging field of massively parallel sequencing

Rebecca S. Just et al.

FORENSIC SCIENCE INTERNATIONAL-GENETICS (2015)

Article Biochemistry & Molecular Biology

Mitochondrial ND3 G10398A mutation: a biomarker for breast cancer

Y. Yu et al.

GENETICS AND MOLECULAR RESEARCH (2015)

Article Biochemistry & Molecular Biology

Global variability in gene expression and alternative splicing is modulated by mitochondrial content

Raul Guantes et al.

GENOME RESEARCH (2015)

Article Biochemistry & Molecular Biology

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju et al.

GENOME RESEARCH (2015)

Article Biochemistry & Molecular Biology

A comprehensive characterization of mitochondrial DNA mutations in glioblastoma multiforme

Michele Vidone et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors

Xiaonan Zhang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Article Cell Biology

Mitoepigenetics: The different shades of grey

Sourav Ghosh et al.

MITOCHONDRION (2015)

Review Biotechnology & Applied Microbiology

How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models

M. W. van Gisbergen et al.

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2015)

Review Genetics & Heredity

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

James B. Stewart et al.

NATURE REVIEWS GENETICS (2015)

Article Multidisciplinary Sciences

Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations

Mingkun Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Why chloroplasts and mitochondria retain their own genomes and genetic systems: Colocation for redox regulation of gene expression

John F. Allen

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Medicine, Research & Experimental

Cancer: Mitochondrial Origins

George B. Stefano et al.

MEDICAL SCIENCE MONITOR (2015)

Review Medicine, General & Internal

Role of mtDNA-related mitoepigenetic phenomena in cancer

Andre Ferreira et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Genetics & Heredity

PhyloTree Build 17: Growing the human mitochondrial DNA tree

Mannis van Oven

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES (2015)

Article Cell Biology

Cancer as a mitochondrial metabolic disease

Thomas N. Seyfried

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2015)

Article Geriatrics & Gerontology

In D-loop: 40 years of mitochondrial 7S DNA

Thomas J. Nicholls et al.

EXPERIMENTAL GERONTOLOGY (2014)

Article Biochemistry & Molecular Biology

Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment

Luisa Iommarini et al.

HUMAN MOLECULAR GENETICS (2014)

Review Genetics & Heredity

Mitochondrial DNA Rearrangements in Health and Disease-A Comprehensive Study

Joana Damas et al.

HUMAN MUTATION (2014)

Article Gastroenterology & Hepatology

Somatic alterations in mitochondrial DNA and mitochondrial dysfunction in gastric cancer progression

Hsin-Chen Lee et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Review Oncology

Hypermutation in human cancer genomes: footprints and mechanisms

Steven A. Roberts et al.

NATURE REVIEWS CANCER (2014)

Article Toxicology

Mitochondrial DNA Somatic Mutation in Cancer

Aekyong Kim

TOXICOLOGICAL RESEARCH (2014)

Review Biochemistry & Molecular Biology

Mitochondrial DNA mutations and breast tumorigenesis

Neelu Yadav et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2013)

Article Biochemistry & Molecular Biology

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes

Tae-Min Kim et al.

Article Biochemistry & Molecular Biology

Universal heteroplasmy of human mitochondrial DNA

Brendan A. I. Payne et al.

HUMAN MOLECULAR GENETICS (2013)

Review Endocrinology & Metabolism

Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool

Vito Iacobazzi et al.

MOLECULAR GENETICS AND METABOLISM (2013)

Article Multidisciplinary Sciences

Signatures of mutational processes in human cancer

Ludmil B. Alexandrov et al.

NATURE (2013)

Review Multidisciplinary Sciences

Cancer Genome Landscapes

Bert Vogelstein et al.

SCIENCE (2013)

Article Cell Biology

Deciphering Signatures of Mutational Processes Operative in Human Cancer

Ludmil B. Alexandrov et al.

CELL REPORTS (2013)

Review Biochemistry & Molecular Biology

The landscape of mitochondrial DNA variation in human colorectal cancer on the background of phylogenetic knowledge

Katarzyna Skonieczna et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2012)

Article Oncology

Mitochondrial Copy Number Is Associated with Colorectal Cancer Risk

Bharat Thyagarajan et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2012)

Article Oncology

Mitochondrial DNA Sequence Variation and Risk of Pancreatic Cancer

Ernest T. Lam et al.

CANCER RESEARCH (2012)

Article Biochemistry & Molecular Biology

Mitochondrial regulation of epigenetics and its role in human diseases

Sheroy Minocherhomji et al.

EPIGENETICS (2012)

Review Genetics & Heredity

Human mitochondrial DNA: roles of inherited and somatic mutations

Eric A. Schon et al.

NATURE REVIEWS GENETICS (2012)

Article Multidisciplinary Sciences

Spectrum of somatic mitochondrial mutations in five cancers

Tatianna C. Larman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Biochemistry & Molecular Biology

Recent advances in apoptosis, mitochondria and drug resistance in cancer cells

Inthrani R. Indran et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Oncology

Evaluating mitochondrial DNA in patients with breast cancer and benign breast disease

Lijun Shen et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2011)

Article Genetics & Heredity

Somatic Mutations throughout the Entire Mitochondrial Genome Are Associated with Elevated PSA Levels in Prostate Cancer Patients

Anita Kloss-Brandstaetter et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2010)

Article Genetics & Heredity

The pattern of natural selection in somatic cancer mutations of human mtDNA

Pete Stafford et al.

JOURNAL OF HUMAN GENETICS (2010)

Article Multidisciplinary Sciences

Heteroplasmic mitochondrial DNA mutations in normal and tumour cells

Yiping He et al.

NATURE (2010)

Article Gastroenterology & Hepatology

High Rate of Mutation in Mitochondrial DNA Displacement Loop Region in Human Colorectal Cancer

Mansoureh Akouchekian et al.

DISEASES OF THE COLON & RECTUM (2009)

Article Biochemistry & Molecular Biology

mtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints

Ilia Zhidkov et al.

GENOME RESEARCH (2009)

Article Biochemistry & Molecular Biology

Circos: An information aesthetic for comparative genomics

Martin Krzywinski et al.

GENOME RESEARCH (2009)

Article Biochemistry & Molecular Biology

Analysis Association between Mitochondrial Genome Instability and Xenobiotic Metabolizing Genes in Human Breast Cancer

Walter H. Pavicic et al.

MOLECULAR MEDICINE (2009)

Review Multidisciplinary Sciences

The cancer genome

Michael R. Stratton et al.

NATURE (2009)

Article Multidisciplinary Sciences

Following Mitochondrial Footprints through a Long Mucosal Path to Lung Cancer

Santanu Dasgupta et al.

PLOS ONE (2009)

Article Multidisciplinary Sciences

A mitochondrial DNA mutation linked to colon cancer results in proton leaks in cytochrome c oxidase

Ida Namslauer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini et al.

Article Biochemistry & Molecular Biology

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis

Kaori Ishikawa et al.

FEBS LETTERS (2008)

Article Genetics & Heredity

Mitochondrial DNA variant interactions modify breast cancer risk

Daniel Covarrubias et al.

JOURNAL OF HUMAN GENETICS (2008)

Review Genetics & Heredity

Cancer epigenomics: DNA methylomes and histone-modification maps

Manel Esteller

NATURE REVIEWS GENETICS (2007)

Review Biochemistry & Molecular Biology

Mitochondrial mutations in cancer

M. Brandon et al.

ONCOGENE (2006)

Article Biochemistry & Molecular Biology

Mutation hot spots in mammalian mitochondrial DNA

N Galtier et al.

GENOME RESEARCH (2006)

Article Medicine, General & Internal

A critical reassessment of the role of mitochondria in tumorigenesis

A Salas et al.

PLOS MEDICINE (2005)

Article Oncology

Clinical value of mitochondrial mutations in colorectal cancer

A Lièvre et al.

JOURNAL OF CLINICAL ONCOLOGY (2005)

Review Genetics & Heredity

Mitochondrial DNA mutations in human disease

RW Taylor et al.

NATURE REVIEWS GENETICS (2005)

Article Multidisciplinary Sciences

mtDNA mutations increase tumorigenicity in prostate cancer

JA Petros et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biotechnology & Applied Microbiology

Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

HC Lee et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2004)

Article Genetics & Heredity

Hypervariable sites in the mtDNA control region are mutational hotspots

M Stoneking

AMERICAN JOURNAL OF HUMAN GENETICS (2000)

Article Multidisciplinary Sciences

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

MS Fliss et al.

SCIENCE (2000)