Journal
CANCERS
Volume 9, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/cancers9020016
Keywords
EGF signaling; Drosophila development; RAS; RAF; MAP kinase; MEK
Categories
Funding
- Academic Research Fund [MOE2014-T2-2-039]
- Yale-NUS Bridging [IG15-B001]
Ask authors/readers for more resources
EGF signaling is a well-known oncogenic pathway in animals. It is also a key developmental pathway regulating terminal and dorsal-ventral patterning along with many other aspects of embryogenesis. In this review, we focus on the diverse roles for the EGF pathway in Drosophila embryogenesis. We review the existing body of evidence concerning EGF signaling in Drosophila embryogenesis focusing on current uncertainties in the field and areas for future study. This review provides a foundation for utilizing the Drosophila model system for research into EGF effects on cancer.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available