4.7 Article

Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome

Journal

EMERGING INFECTIOUS DISEASES
Volume 22, Issue 11, Pages 1953-1956

Publisher

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2211.160956

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Funding

  1. Maranhao State Health Department
  2. Brazil's National Research Council (CNPq)
  3. Maranhao State Research Foundation (FAPEMA)

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We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1-8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with increasingly negative z-scores, pyramidal/extrapyramidal symptoms, and epilepsy.

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