Journal
ONCOLOGY-NEW YORK
Volume 30, Issue 10, Pages 923-933Publisher
UBM MEDICA
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Funding
- Accuray
- Angiochem
- BBB Therapeutics
- Cascadian Therapeutics
- Geron Corporation
- Lilly
- Merck
- Merrimack Pharmaceuticals
- Novartis
- Puma Biotechnology
- Sanofi/BiPar Sciences
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This review summarizes the most up-to-date approach to the multidisciplinary management of patients with breast cancer brain metastases. A brief overview of the epidemiology and biology of breast cancer brain metastasis is provided. The perspectives of radiation oncology, neurosurgery, and medical oncology and landmark studies from each discipline are all discussed. We also offer practical tips to help guide the treating physician, including data on antiseizure medications. Finally, we introduce the concept of a multidisciplinary clinic that combines input from medical and radiation oncology, neurosurgery, and support services, which we developed at the University of North Carolina as a coordinated and optimal approach to the management of patients with this complex disease.
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