Related references
Note: Only part of the references are listed.Low-Dose Pesticide Mixture Induces Senescence in Normal Mesenchymal Stem Cells (MSC) and Promotes Tumorigenic Phenotype in Premalignant MSC
Mazene Hochane et al.
STEM CELLS (2017)
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
Birgit Ritschka et al.
GENES & DEVELOPMENT (2017)
Rejuvenation of mucosal immunosenescence by adipose tissue-derived mesenchymal stem cells
Akitoshi Tsuruhara et al.
INTERNATIONAL IMMUNOLOGY (2017)
Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
Meenakshi Gaur et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Opposing activities of oncogenic MIR17HG and tumor suppressive MIR100HG clusters and their gene targets regulate replicative senescence in human adult stem cells
Mary F. Lopez et al.
NPJ AGING AND MECHANISMS OF DISEASE (2017)
Role of leptin as a link between metabolism and the immune system
Antonio Perez-Perez et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2017)
Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle
Aurelie Chiche et al.
CELL STEM CELL (2017)
Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia
Jesus M. Pradillo et al.
BRAIN BEHAVIOR AND IMMUNITY (2017)
Secretome of human bone marrow mesenchymal stem cells: an emerging player in lung cancer progression and mechanisms of translation initiation
Oshrat Attar-Schneider et al.
TUMOR BIOLOGY (2016)
Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
Servet Ozcan et al.
AGING-US (2016)
NKG2D ligands mediate immunosurveillance of senescent cells
Adi Sagiv et al.
AGING-US (2016)
A lack of Fas/FasL signalling leads to disturbances in the antiviral response during ectromelia virus infection
K. Bien et al.
ARCHIVES OF VIROLOGY (2016)
Inflammasome Complexes: Emerging Mechanisms and Effector Functions
Vijay A. K. Rathinam et al.
CELL (2016)
The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation
Deepika Sharma et al.
JOURNAL OF CELL BIOLOGY (2016)
Derepression of hTERT gene expression promotes escape from oncogene-induced cellular senescence
Priyanka L. Patel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
Lluc Mosteiro et al.
SCIENCE (2016)
Mechanisms of mesenchymal stem/stromal cell function
Jeffrey L. Spees et al.
STEM CELL RESEARCH & THERAPY (2016)
Comparison of the Biological Characteristics of Mesenchymal Stem Cells Derived from Bone Marrow and Skin
Ruifeng Liu et al.
STEM CELLS INTERNATIONAL (2016)
ASPL-TFE3 Oncoprotein Regulates Cell Cycle Progression and Induces Cellular Senescence by Up-Regulating p21
Naoko Ishiguro et al.
NEOPLASIA (2016)
Adipose-Derived Mesenchymal Stem Cells Restore Impaired Mucosal Immune Responses in Aged Mice
Kazuyoshi Aso et al.
PLOS ONE (2016)
Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline
Estefania Carrasco-Garcia et al.
AGING CELL (2015)
Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1a-Dependent Senescence Associated Secretory Phenotype
Sarah E. Gardner et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)
Mitochondria: Are they causal players in cellular senescence?
Clara Correia-Melo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations
Chih-Chiang Chen et al.
CELL (2015)
The interleukin (IL)-1 cytokine family - Balance between agonists and antagonists in inflammatory diseases
Jennifer Palomo et al.
CYTOKINE (2015)
Cellular senescence in aging and age-related disease: from mechanisms to therapy
Bennett G. Childs et al.
NATURE MEDICINE (2015)
Concise Review: Quiescence in Adult Stem Cells: Biological Significance and Relevance to Tissue Regeneration
Mohammad Rumman et al.
STEM CELLS (2015)
Senescence-associated inflammatory responses: aging and cancer perspectives
Audrey Lasry et al.
TRENDS IN IMMUNOLOGY (2015)
Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic
Nils H. Nicolay et al.
ONCOTARGET (2015)
Transcriptional profiling of interleukin-2-primed human adipose derived mesenchymal stem cells revealed dramatic changes in stem cells response imposed by replicative senescence
Ping Niu et al.
ONCOTARGET (2015)
Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells
Stefania Capasso et al.
ONCOTARGET (2015)
Registered report: Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
Samrrah Raouf et al.
ELIFE (2015)
Adipokines as Drug Targets in Diabetes and Underlying Disturbances
Vincius Andrade-Oliveira et al.
JOURNAL OF DIABETES RESEARCH (2015)
Leptin and Neutrophil-Activating Peptide 2 Promote Mesenchymal Stem Cell Senescence Through Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway in Patients With Systemic Lupus Erythematosus
Haifeng Chen et al.
ARTHRITIS & RHEUMATOLOGY (2015)
T cells from autoimmune patients display reduced sensitivity to immunoregulation by mesenchymal stem cells: Role of IL-2
Eyal Ben-Ami et al.
AUTOIMMUNITY REVIEWS (2014)
p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer
Darjus F. Tschaharganeh et al.
CELL (2014)
Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation
Xin Cai et al.
CELL (2014)
Geroconversion: irreversible step to cellular senescence
Mikhail V. Blagosklonny
CELL CYCLE (2014)
The architect who never sleeps: Tumor-induced plasticity
Julia Varga et al.
FEBS LETTERS (2014)
Cellular senescence and its effector programs
Rafik Salama et al.
GENES & DEVELOPMENT (2014)
Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2
Pei-Min Chen et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2014)
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
Alberto Baroja-Mazo et al.
NATURE IMMUNOLOGY (2014)
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
Bernardo S. Franklin et al.
NATURE IMMUNOLOGY (2014)
Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose Homeostasis
Yuwei Jiang et al.
CELL REPORTS (2014)
The life and fate of mesenchymal stem cells
Elke Eggenhofer et al.
FRONTIERS IN IMMUNOLOGY (2014)
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
Marco Cecco et al.
AGING CELL (2013)
A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism
Ariel Pribluda et al.
CANCER CELL (2013)
Roles and mechanisms of cellular senescence in regulation of tissue homeostasis
Naoko Ohtani et al.
CANCER SCIENCE (2013)
Non-Cell-Autonomous Tumor Suppression by p53
Amaia Lujambio et al.
CELL (2013)
Programmed Cell Senescence during Mammalian Embryonic Development
Daniel Munoz-Espin et al.
CELL (2013)
Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
Mekayla Storer et al.
CELL (2013)
Mechanisms that Regulate Stem Cell Aging and Life Span
Robert A. J. Signer et al.
CELL STEM CELL (2013)
Probing the depths of cellular senescence
Darren J. Baker et al.
JOURNAL OF CELL BIOLOGY (2013)
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
Shin Yoshimoto et al.
NATURE (2013)
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
Joanna Kaplon et al.
NATURE (2013)
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
Juan Carlos Acosta et al.
NATURE CELL BIOLOGY (2013)
Control of cell cycle transcription during G1 and S phases
Cosetta Bertoli et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine
Matthew B. Murphy et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2013)
Intestinal stem cell injury and protection during cancer therapy
Jian Yu
TRANSLATIONAL CANCER RESEARCH (2013)
Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells
Mary F. Lopez et al.
AGING-US (2012)
Immunomodulatory Properties of Mesenchymal Stem Cells and Their Therapeutic Applications
TacGhee Yi et al.
ARCHIVES OF PHARMACAL RESEARCH (2012)
B-Raf Activation Cooperates with PTEN Loss to Drive c-Myc Expression in Advanced Prostate Cancer
Jingqiang Wang et al.
CANCER RESEARCH (2012)
Immune surveillance of senescent cells-biological significance in cancer- and non-cancer pathologies
Lisa Hoenicke et al.
CARCINOGENESIS (2012)
Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis
Liesbeth C. W. Vredeveld et al.
GENES & DEVELOPMENT (2012)
An essential role for the DNA breakage-repair protein Ku80 in programmed DNA rearrangements in Tetrahymena thermophila
I-Ting Lin et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Radiation-inducible Immunotherapy for Cancer: Senescent Tumor Cells as a Cancer Vaccine
Yuru Meng et al.
MOLECULAR THERAPY (2012)
Inflammasomes in health and disease
Till Strowig et al.
NATURE (2012)
Hepatocyte growth factor mediates mesenchymal stem cell-induced recovery in multiple sclerosis models
Lianhua Bai et al.
NATURE NEUROSCIENCE (2012)
Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling
Sumati Rajagopalan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
T-Cell Tolerance: Central and Peripheral
Yan Xing et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Mesenchymal Stem Cells: Mechanisms of Inflammation
Nora G. Singer et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)
Programmed Cell Death in Animal Development and Disease
Yaron Fuchs et al.
CELL (2011)
Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC
Ralf Hass et al.
CELL COMMUNICATION AND SIGNALING (2011)
Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal
Jianrong Wang et al.
CELL CYCLE (2011)
Protective Capacity of Memory CD8+ T Cells Is Dictated by Antigen Exposure History and Nature of the Infection
Jeffrey C. Nolz et al.
IMMUNITY (2011)
Inhibition of Classic Signaling Is a Novel Function of Soluble Glycoprotein 130 (sgp130), Which Is Controlled by the Ratio of Interleukin 6 and Soluble Interleukin 6 Receptor
Christoph Garbers et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases
Gayani Nadika Pitiyage et al.
JOURNAL OF PATHOLOGY (2011)
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
Tae-Won Kang et al.
NATURE (2011)
Pro-senescence therapy for cancer treatment
Caterina Nardella et al.
NATURE REVIEWS CANCER (2011)
Mesenchymal stem cells as anti-inflammatories: Implications for treatment of Duchenne muscular dystrophy
Thomas E. Ichim et al.
CELLULAR IMMUNOLOGY (2010)
Recruitment of endogenous bone marrow mesenchymal stem cells towards injured liver
Ye Chen et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Kinetic Properties of ASC Protein Aggregation in Epithelial Cells
Jun Cheng et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
Andrea Alimonti et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Loss of CD4+ T Cell IL-6R Expression during Inflammation Underlines a Role for IL-6 Trans Signaling in the Local Maintenance of Th17 Cells
Gareth W. Jones et al.
JOURNAL OF IMMUNOLOGY (2010)
Involvement of IFN-γ and perforin, but not Fas/FasL interactions in regulatory T cell-mediated suppression of experimental autoimmune encephalomyelitis
Tara Beeston et al.
JOURNAL OF NEUROIMMUNOLOGY (2010)
Therapy-Induced Senescence in Cancer
Jonathan A. Ewald et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
The Negative Co-Signaling Molecule B7-H4 Is Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Mediates its T-Cell Modulatory Activity
Qun Xue et al.
STEM CELLS AND DEVELOPMENT (2010)
Inflammatory networks during cellular senescence: causes and consequences
Adam Freund et al.
TRENDS IN MOLECULAR MEDICINE (2010)
Genetic Control of Programmed Cell Death During Animal Development
Barbara Conradt
ANNUAL REVIEW OF GENETICS (2009)
Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice
Nathalie Dhomen et al.
CANCER CELL (2009)
Rb Regulates DNA Damage Response and Cellular Senescence through E2F-Dependent Suppression of N-Ras Isoprenylation
Awad Shamma et al.
CANCER CELL (2009)
Reciprocal Requirements for EDA/EDAR/NF-κB and Wnt/β-Catenin Signaling Pathways in Hair Follicle Induction
Yuhang Zhang et al.
DEVELOPMENTAL CELL (2009)
Therapeutic Targeting of IL-6 Trans Signaling Counteracts STAT3 Control of Experimental Inflammatory Arthritis
Mari A. Nowell et al.
JOURNAL OF IMMUNOLOGY (2009)
Myeloid-Derived Suppressor Cells Down-Regulate L-Selectin Expression on CD4+ and CD8+ T Cells
Erica M. Hanson et al.
JOURNAL OF IMMUNOLOGY (2009)
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
Francis Rodier et al.
NATURE CELL BIOLOGY (2009)
Senescence-messaging secretome: SMS-ing cellular stress
Thomas Kuilman et al.
NATURE REVIEWS CANCER (2009)
Response of mesenchymal stem cells to the biomechanical environment of the endothelium on a flexible tubular silicone substrate
Eoin D. O'Cearbhaill et al.
BIOMATERIALS (2008)
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
Thomas Kuilman et al.
CELL (2008)
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7
Narendra Wajapeyee et al.
CELL (2008)
Chemokine signaling via the CXCR2 receptor reinforces senescence
Juan C. Acosta et al.
CELL (2008)
Senescence of activated stellate cells limits liver fibrosis
Valery Krizhanovsky et al.
CELL (2008)
Posttranslational regulation of Fas ligand function
Matthias Voss et al.
Cell Communication and Signaling (2008)
Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide
Guangwen Ren et al.
CELL STEM CELL (2008)
Cell-to-cell communication: Time and length scales of ligand internalization in cultures of suspended cells
Alexander M. Berezhkovskii et al.
JOURNAL OF CHEMICAL PHYSICS (2008)
Tumor-induced CD11b(+)Gr-1(+) myeloid cells suppress T cell Sensitization in tumor-draining lymph nodes
Satoshi Watanabe et al.
JOURNAL OF IMMUNOLOGY (2008)
Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
Jean-Philippe Coppe et al.
PLOS BIOLOGY (2008)
Living on a break: cellular senescence as a DNA-damage response
Fabrizio d'Adda di Fagagna
NATURE REVIEWS CANCER (2008)
Transgenic blockade of interleukin 6 transsignaling abrogates inflammation
Bjorn Rabe et al.
BLOOD (2008)
Mesenchymal stem cells in health and disease
Antonio Uccelli et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Targeting selectins and selectin ligands in inflammation and cancer
Steven R. Barthel et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
Human mesenchymal stem cells promote survival of T cells in a quiescent state
Federica Benvenuto et al.
STEM CELLS (2007)
The in vitro migration capacity of human bone marrow mesenchymal stem cells:: Comparison of chemokine and growth factor chemotactic activities
Adriana Lopez Ponte et al.
STEM CELLS (2007)
Neuroepithelial cells supply an initial transient wave of MSC differentiation
Yasuhiro Takashima et al.
CELL (2007)
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
Joao F. Passos et al.
PLOS BIOLOGY (2007)
Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion
Dan Liu et al.
CANCER RESEARCH (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
A key role of leptin in the control of regulatory T cell proliferation
Veronica De Rosa et al.
IMMUNITY (2007)
Non-developmentally programmed cell death in Caenorhabditis elegans
Nikos Kourtis et al.
SEMINARS IN CANCER BIOLOGY (2007)
Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
Akiko Takahashi et al.
NATURE CELL BIOLOGY (2006)
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
Viktor Janzen et al.
NATURE (2006)
Inhibition of T cell homing by down-regulation of CD62L and the induction of a Th-2 response as a method to prevent acute allograft rejection in mice
Christian Stremmel et al.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2006)
Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
Roderik M. Kortlever et al.
NATURE CELL BIOLOGY (2006)
The role of leptin in innate and adaptive immune responses
Eiva Bernotiene et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all
Jesus Gil et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
Oncogene-induced senescence as an initial barrier in lymphoma development
M Braig et al.
NATURE (2005)
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
ZB Chen et al.
NATURE (2005)
BRAFE600-associated senescence-like cell cycle arrest of human naevi
C Michaloglou et al.
NATURE (2005)
Elevated soluble ICAM-1 levels induce immune deficiency and increase adiposity in mice
HW Wang et al.
FASEB JOURNAL (2005)
Bone marrow mesenchymal stem cefls induce division arrest anergy of activated T cells
S Glennie et al.
BLOOD (2005)
Human mesenchymal stem cells modulate allogeneic immune cell responses
S Aggarwal et al.
BLOOD (2005)
Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation
K Ley et al.
NATURE REVIEWS IMMUNOLOGY (2004)
Mapping of the leptin binding sites and design of a leptin antagonist
F Peelman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21CIP1, but not p16INK4a
U Herbig et al.
MOLECULAR CELL (2004)
The Fas/Fas ligand system and cancer
VM Abrahams et al.
MOLECULAR BIOTECHNOLOGY (2003)
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
J Sage et al.
NATURE (2003)
The ins and outs of leptin receptor activation
L Zabeau et al.
FEBS LETTERS (2003)
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
M Narita et al.
CELL (2003)
The role of selectins in inflammation and disease
K Ley
TRENDS IN MOLECULAR MEDICINE (2003)
Reversal of senescence in mouse fibroblasts through lentiviral in suppression of p53
AMG Dirac et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation
ZG Tian et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
M Di Nicola et al.
BLOOD (2002)
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
CA Schmitt et al.
CELL (2002)
Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
A Bartholomew et al.
EXPERIMENTAL HEMATOLOGY (2002)
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
A Krtolica et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Stem cells and aging: expanding the possibilities
MS Rao et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2001)
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
T Jostock et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
Epithelial-mesenchymal interactions in the pathogenesis of asthma
ST Holgate et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2000)