Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 4, Issue 4, Pages 545-554Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6qo00533k
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- Program for Innovative Research Team from Zhengzhou [131PCXTD605]
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An efficient silver-catalyzed intermolecular decarboxylative arylation of quinolines has been developed using cheap aromatic carboxylic acids as arylating reagents under microwave irradiation. The reaction demonstrates a broad substrate scope and excellent functional group tolerance. This method provided an effective and easy way to synthesize arylated quinoline derivatives. The radical trapping experiments showed that this process involved the radical mechanism.
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