Journal
ORGANIC CHEMISTRY FRONTIERS
Volume 4, Issue 3, Pages 413-416Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6qo00670a
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Funding
- National Natural Science Foundation of China [21272028, 21572025, 21672028]
- Key University Science Research Project of Jiangsu Province [15KJA150001]
- Jiangsu Key Laboratory of Advanced Catalytic Materials Technology [BM2012110]
- Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Changzhou University
- Research Innovation Program for College Graduates of Jiangsu Province [KYLZ15_1118]
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A three-component reaction of quaternary ammonium salts, N-substituted formamides and aqueous sodium disulfide was developed, leading to aryl/heteroaryl thioamides in moderate to good yields with good functional group compatibility. This procedure was featured with the combination of three reaction partners, rendering an important complementary to the previously reported methods for the synthesis of aryl thioamides, and was beneficial to the chemistry of functional group transformations. No external oxidant was required in this procedure.
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