Journal
EUROPEAN RESPIRATORY JOURNAL
Volume 46, Issue 5, Pages 1281-1289Publisher
EUROPEAN RESPIRATORY SOC JOURNALS LTD
DOI: 10.1183/13993003.01699-2014
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Funding
- Fondo de Investigacion Sanitaria [FIS PI052292, PI052486, PI052302]
- Spanish Society of Pneumology and Thoracic Surgery [SEPAR 2004/136, SEPAR 2002/137]
- Fondo de Investigacion Sanitaria, Ministry of Health, Spain [FIS PI020541]
- Agenda d'Avaluacio de Tecnologia i Recerca Mediques, Catalonia Government [AATRM 035/20/02]
- Catalan Foundation of Pneumology (FUCAP Beca Maria Rava)
- Red RESPIRA [RTIC C03/11]
- Red RCESP [RTIC C03/09]
- Fundacio La Marato de TV3 [041110]
- DURSI [2005SGR00392]
- Novartis Farmaceutica (Spain)
- AstraZeneca Farmaceutica (Spain)
- Instituto de Salud Carlos III, Ministry of Health, Spain
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The present study aims to disentangle the independent effects of the quantity and the intensity of physical activity on the risk reduction of chronic obstructive pulmonary disease (COPD) hospitalisations. 177 patients from the Phenotype Characterization and Course of COPD (PAC-COPD) cohort (mean +/- SD age 71 +/- 8 years, forced expiratory volume in 1 s 52 +/- 16% predicted) wore the Sense Wear Pro 2 Armband accelerometer (Body Media, Pittsburgh, PA, USA) for eight consecutive days, providing data on quantity (steps per day, physically active days and daily active time) and intensity (average metabolic equivalent tasks) of physical activity. Information on COPD hospitalisations during follow-up (2.5 +/- 0.8 years) was obtained from validated centralised datasets. During follow-up 67 (38%) patients were hospitalised. There was an interaction between quantity and intensity of physical activity in their effects on COPD hospitalisation risk. After adjusting for potential confounders in the Cox regression model, the risk of COPD hospitalisation was reduced by 20% (hazard ratio (HR) 0.79, 95% CI 0.67-0.93; p=0.005) for every additional 1000 daily steps at low average intensity. A greater quantity of daily steps at high average intensity did not influence the risk of COPD hospitalisations (HR 1.01, p=0.919). Similar results were found for the other measures of quantity of physical activity. Greater quantity of low-intensity physical activity reduces the risk of COPD hospitalisation, but high-intensity physical activity does not produce any risk reduction.
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