4.7 Article

ESGAR consensus statement on liver MR imaging and clinical use of liver-specific contrast agents

Journal

EUROPEAN RADIOLOGY
Volume 26, Issue 4, Pages 921-931

Publisher

SPRINGER
DOI: 10.1007/s00330-015-3900-3

Keywords

Liver; Biliary tract; Magnetic resonance imaging; Contrast media; Delphi technique

Funding

  1. Donseo Medical
  2. CMS
  3. Acuzen
  4. Starmed Ltd.
  5. RF MEDICAL
  6. Bayer Healthcare
  7. Siemens
  8. Bracco
  9. Bayer
  10. Guerbet

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Objectives To develop a consensus and provide updated recommendations on liver MR imaging and the clinical use of liver-specific contrast agents. Methods The European Society of Gastrointestinal and Abdominal Radiology (ESGAR) formed a multinational European panel of experts, selected on the basis of a literature review and their leadership in the field of liver MR imaging. A modified Delphi process was adopted to draft a list of statements. Descriptive and Cronbach's statistics were used to rate levels of agreement and internal reliability of the consensus. Results Three Delphi rounds were conducted and 76 statements composed on MR technique (n = 17), clinical application of liver-specific contrast agents in benign, focal liver lesions (n = 7), malignant liver lesions in non-cirrhotic (n = 9) and in cirrhotic patients (n = 18), diffuse and vascular liver diseases (n = 12), and bile ducts (n = 13). The overall mean score of agreement was 4.84 (SD +/- 0.17). Full consensus was reached in 22 % of all statements in all working groups, with no full consensus reached on diffuse and vascular diseases. Conclusions The consensus provided updated recommendations on the methodology, and clinical indications, of MRI with liver specific contrast agents in the study of liver diseases.

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