4.6 Review

Gold Nanoparticles for Diagnostics: Advances towards Points of Care

Journal

DIAGNOSTICS
Volume 6, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/diagnostics6040043

Keywords

gold nanoparticles; diagnosis; point-of-need; biomolecular sensing

Funding

  1. Fundacao para a Ciencia e Tecnologia (FCT/MEC) [Pest-C/EQB/LA0006/2011, UID/Multi/04378/2013, SFRH/BD/87836/2012, PD/BD/105734/2014, JPI/0003/2013-TRACE]
  2. Fundação para a Ciência e a Tecnologia [PD/BD/105734/2014, SFRH/BD/87836/2012] Funding Source: FCT

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The remarkable physicochemical properties of gold nanoparticles (AuNPs) have prompted developments in the exploration of biomolecular interactions with AuNP-containing systems, in particular for biomedical applications in diagnostics. These systems show great promise in improving sensitivity, ease of operation and portability. Despite this endeavor, most platforms have yet to reach maturity and make their way into clinics or points of care (POC). Here, we present an overview of emerging and available molecular diagnostics using AuNPs for biomedical sensing that are currently being translated to the clinical setting.

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