Journal
EUROPEAN RADIOLOGY
Volume 25, Issue 11, Pages 3200-3206Publisher
SPRINGER
DOI: 10.1007/s00330-015-3739-7
Keywords
Diagnostic imaging; Multidetector computed tomography; Pulmonary arteries; Pulmonary embolism; Cancer
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To prospectively assess prevalence/characteristics of clinically unsuspected pulmonary embolism (PE) in cancer patients undergoing follow-up chest MDCT and investigate MDCT protocol. We evaluated 1013 oncologic patients. MDCT images at 5 and 1.25 mm thickness were independently evaluated. Pulmonary artery opacification degree was assessed. Presence, level, and site of PE were reported. Type of malignancy and metastases were reported for PE-positive patients. After excluding 1.4 % (14/1013) of examinations due to inadequate vessel opacification, 999 patients (572 male; mean age:68 +/- 12 years; range:26-93 years) entered the study. Prevalence of PE was 5 %. There was significant improvement in the sensitivity for both readers in the evaluation of 1.25 mm compared to 5 mm images (46-50 % to 82-92 %). 30 % (15/51) PE were not described by the radiologist in the prospectively issued report; 53 % (27/51) of PE were segmental, 72.5 % (37/51) unilateral. The right lower lobe was the most involved (59 %). 27 % patients had colon cancer, 18 % lung cancer. Among PE-positive patients (25 male; mean age 70 +/- 10 years; range:44-87 years), 25 % (13/51) had lung cancer, 15 % (8/51) colon cancer. Thin reconstructions are essential for PE diagnosis, regardless of reader experience. Regarding oncologic patients, incidental PE diagnosis influences anticoagulation therapy. aEuro cent CT pulmonary angiography is the gold standard for PE diagnosis. aEuro cent Cancer and oncological treatments are risk factors for PE. aEuro cent The prevalence of unsuspected PE was 5 %. aEuro cent Thin reconstructions are essential for PE diagnosis regardless of reader experience. aEuro cent In oncologic patients, PE diagnosis influences anticoagulation therapy.
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