Journal
CHEMCATCHEM
Volume 8, Issue 24, Pages 3796-3803Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cctc.201601051
Keywords
acetic acid bacteria; biocatalysis; desymmetrization; enantioselectivity; oxidation
Categories
Funding
- Fondazione Cariplo [2014-0568]
Ask authors/readers for more resources
The stereoselective desymmetrisation of achiral 2-alkyl-1,3-diols is performed by oxidation of one of the two enantiotopic primary alcohol moieties by means of Acetobacter aceti MIM 2000/28 to afford the corresponding chiral 2-hydroxymethyl alkanoic acids (up to 94% ee). The procedure, carried out in aqueous medium under mild conditions of pH, temperature and pressure, contributes to enlarge the portfolio of enzymatic oxidations available to organic chemists for the development of sustainable manufacturing processes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available