Fabrication of Alginate Fibers Loaded with Silver Nanoparticles Biosynthesized via Dolcetto Grape Leaves (Vitis vinifera cv.): Morphological, Antimicrobial Characterization and In Vitro Release Studies

The use of silver nanoparticles to enable high-efficient antimicrobial concepts have frequently been described with great potentials for wound healing in scientific literature. Among different synthesis methods, green synthesis of silver nanoparticles can be easy and a producible method. The fabrication of alginate fibers integrated with silver nanoparticles (AgNPs) synthesized from natural Dolcetto grape leaves, using the wet spinning method was carried out. AgNPs were synthesized by the main ingredient (flavonoids) present in Dolcetto grape leaves acted as a reducing agent. The alginate fibers were characterized by SEM and FTIR. The resulting fibers were confirmed for their controlled drug release, robust mechanical and antimicrobial properties, for potential applications in alginate based AgNPs wound dressings.