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Remote Diffusion-Weighted Imaging Lesions in Intracerebral Hemorrhage: Characteristics, Mechanisms, Outcomes, and Therapeutic Implications

Journal

FRONTIERS IN NEUROLOGY
Volume 8, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fneur.2017.00678

Keywords

intracerebral hemorrhage; secondary brain injury; remote diffusion-weighed imaging lesions; microangiopathy; blood pressure lowering

Funding

  1. National Natural Science Foundation of China (NSFC) [81471168, 81500991]
  2. Foundation of Zhejiang Educational Committee [Y201738067]
  3. Medical Scientific Research Foundation of Zhejiang Province [2018250144]

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Spontaneous intracerebral hemorrhage (ICH) is one of the most fatal form of stroke, with high mortality and disability rate. Small diffusion-weighed imaging lesions are not rare to see in regions remote from the hematoma after ICH and have been generally considered as related with poor outcome. In this review, we described the characteristics of remote ischemic lesions, discussed the possible mechanisms and clinical outcomes of these lesions, and evaluated the potential therapeutic implications.

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