Related references
Note: Only part of the references are listed.Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases
Sinead O'Sullivan et al.
NEUROPHARMACOLOGY (2017)
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock A Retrospective Before-After Study
Paul E. Marik et al.
CHEST (2017)
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Mervyn Singer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)
Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer's disease
Nurgul Aytan et al.
SCIENTIFIC REPORTS (2016)
Effect of FTY720 (fingolimod) on graft survival in renal transplant recipients: a systematic review protocol
Reza Gholamnezhadjafari et al.
BMJ OPEN (2016)
Endotoxemia-induced cytokine-mediated responses of hippocampal astrocytes transmitted by cells of the brain-immune interface
Sanae Hasegawa-Ishii et al.
SCIENTIFIC REPORTS (2016)
Protein tyrosine kinase 6 mediates TNFα-induced endothelial barrier dysfunction
R. J. Haines et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
The blood-brain barrier in neuroimmunology: Tales of separation and assimilation
W. A. Banks
BRAIN BEHAVIOR AND IMMUNITY (2015)
Sphingosin-1-phosphate Receptor 1: a Potential Target to Inhibit Neuroinflammation and Restore the Sphingosin-1-phosphate Metabolism
Zeynab Kolahdooz et al.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2015)
Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells
Simon J. O'Carroll et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Dangerous Leaks: Blood-Brain Barrier Woes in the Aging Hippocampus
Costantino Iadecola
NEURON (2015)
Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
Axel Montagne et al.
NEURON (2015)
Sepsis Is Associated With Altered Cerebral Microcirculation and Tissue Hypoxia in Experimental Peritonitis
Fabio Silvio Taccone et al.
CRITICAL CARE MEDICINE (2014)
Sphingosine 1-phosphate signalling
Karen Mendelson et al.
DEVELOPMENT (2014)
Prominence of Central Sphingosine-1-Phosphate Receptor-1 in Attenuating Aβ-Induced Injury by Fingolimod
Masoumeh Asle-Rousta et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2014)
Acute Neuroinflammation Impairs Context Discrimination Memory and Disrupts Pattern Separation Processes in Hippocampus
Jennifer Czerniawski et al.
JOURNAL OF NEUROSCIENCE (2014)
Complement and blood-brain barrier integrity
Alexander Jacob et al.
MOLECULAR IMMUNOLOGY (2014)
Sphingosine Kinase 1 and Sphingosine-1-Phosphate in Oxidative Stress Evoked by 1-Methyl-4-Phenylpyridinium (MPP plus ) in Human Dopaminergic Neuronal Cells
Joanna Pyszko et al.
MOLECULAR NEUROBIOLOGY (2014)
You Shall Not Pass-tight junctions of the blood brain barrier
Hans-Christian Bauer et al.
FRONTIERS IN NEUROSCIENCE (2014)
Clinical neurophysiological assessment of sepsis-associated brain dysfunction: a systematic review
Koji Hosokawa et al.
CRITICAL CARE (2014)
Sphingosine-1-Phosphate, FTY720, and Sphingosine-1-Phosphate Receptors in the Pathobiology of Acute Lung Injury
Viswanathan Natarajan et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)
Species-Dependent Blood-Brain Barrier Disruption of Lipopolysaccharide: Amelioration by Colistin In Vitro and In Vivo
Liang Jin et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Sepsis-induced brain dysfunction
Nicolas Adam et al.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2013)
Delirium: Definition, Epidemiology, and Diagnosis
Karin J. Neufeld et al.
JOURNAL OF CLINICAL NEUROPHYSIOLOGY (2013)
FTY720 (Fingolimod) Attenuates Beta-amyloid Peptide (Aβ42)-Induced Impairment of Spatial Learning and Memory in Rats
Masoumeh Asle-Rousta et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2013)
Fingolimod: Direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy
Aran Groves et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2013)
Development, maintenance and disruption of the blood-brain barrier
Birgit Obermeier et al.
NATURE MEDICINE (2013)
Fingolimod protects cultured cortical neurons against excitotoxic death
Luisa Di Menna et al.
PHARMACOLOGICAL RESEARCH (2013)
BIOENERGETICS, MITOCHONDRIAL DYSFUNCTION, AND OXIDATIVE STRESS IN THE PATHOPHYSIOLOGY OF SEPTIC ENCEPHALOPATHY
Fernando A. Bozza et al.
SHOCK (2013)
Understanding brain dysfunction in sepsis
Romain Sonneville et al.
ANNALS OF INTENSIVE CARE (2013)
Role of Sphingomyelin Synthesis in Pulmonary Endothelial Cell Cytoskeletal Activation and Endotoxin-Induced Lung Injury
Fatima Anjum et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Intravenous immunoglobulins prevent the breakdown of the blood-brain barrier in experimentally induced sepsis
Figen Esen et al.
CRITICAL CARE MEDICINE (2012)
Morphofunctional Aspects of the Blood-Brain Barrier
Beatrice Nico et al.
CURRENT DRUG METABOLISM (2012)
Increased Ceramide in Brains with Alzheimer's and Other Neurodegenerative Diseases
Valery Filippov et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Drug transport across the blood-brain barrier
William M. Pardridge
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Population Burden of Long-Term Survivorship After Severe Sepsis in Older Americans
Theodore J. Iwashyna et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2012)
Ceramide sphingolipid signaling mediates Tumor Necrosis Factor (TNF)-dependent toxicity via caspase signaling in dopaminergic neurons
Terina N. Martinez et al.
MOLECULAR NEURODEGENERATION (2012)
Sepsis-associated encephalopathy
Teneille E. Gofton et al.
NATURE REVIEWS NEUROLOGY (2012)
Sphingosine Kinase 1 Deficiency Exacerbates LPS-Induced Neuroinflammation
Natalia M. Grin'kina et al.
PLOS ONE (2012)
Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain
Ronald E. Cannon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells
Min Long et al.
JOURNAL OF BIOMEDICAL SCIENCE (2012)
Sphingomyelin synthase 2 (SMS2) deficiency attenuates LPS-induced lung injury
Satish Gowda et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)
Cytokine Signaling Modulates Blood-Brain Barrier Function
Weihong Pan et al.
CURRENT PHARMACEUTICAL DESIGN (2011)
C5a/CD88 signaling alters blood-brain barrier integrity in lupus through nuclear factor-κB
Alexander Jacob et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Caspase signalling controls microglia activation and neurotoxicity
Miguel A. Burguillos et al.
NATURE (2011)
Septic encephalopathy: Inflammation in man and mouse
Alexander Jacob et al.
NEUROCHEMISTRY INTERNATIONAL (2011)
INTERLEUKIN-1β CAUSES LONG-TERM POTENTIATION DEFICIENCY IN A MOUSE MODEL OF SEPTIC ENCEPHALOPATHY
Y. Imamura et al.
NEUROSCIENCE (2011)
Looking at the blood-brain barrier: Molecular anatomy and possible investigation approaches
Filipa Lourenco Cardoso et al.
BRAIN RESEARCH REVIEWS (2010)
Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis
Jerold Chun et al.
CLINICAL NEUROPHARMACOLOGY (2010)
Sepsis-associated encephalopathy and its differential diagnosis
Emanuele Iacobone et al.
CRITICAL CARE MEDICINE (2010)
Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis
Theodore J. Iwashyna et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
Deregulation of sphingolipid metabolism in Alzheimer's disease
Xingxuan He et al.
NEUROBIOLOGY OF AGING (2010)
The blood-brain barrier and immune function and dysfunction
William A. Banks et al.
NEUROBIOLOGY OF DISEASE (2010)
Structure and function of the blood-brain barrier
N. Joan Abbott et al.
NEUROBIOLOGY OF DISEASE (2010)
Expression and regulation of toll-like receptors in cerebral endothelial cells
Peter Nagyoszi et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
REGULATION OF SYNAPTIC STRENGTH BY SPHINGOSINE 1-PHOSPHATE IN THE HIPPOCAMPUS
T. Kanno et al.
NEUROSCIENCE (2010)
Differential regulation of sphingosine kinases 1 and 2 in lung injury
Raj Wadgaonkar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system
Taro Okada et al.
CELLULAR SIGNALLING (2009)
The complement cascade as a therapeutic target in intracerebral hemorrhage
Andrew F. Ducruet et al.
EXPERIMENTAL NEUROLOGY (2009)
Expression of endothelial phosphorylated caveolin-1 is increased in brain injury
S. Nag et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2009)
FTY720 modulates human oligodendrocyte progenitor process extension and survival
Veronique E. Miron et al.
ANNALS OF NEUROLOGY (2008)
Regulation and functions of sphingosine kinases in the brain
Lauren Bryan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
Sphingosine-1-phosphate regulation of mammalian development
Mari Kono et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
Activation of Sphingosine Kinase-1 Reverses the Increase in Lung Vascular Permeability Through Sphingosine-1-Phosphate Receptor Signaling in Endothelial Cells
Mohammad Tauseef et al.
CIRCULATION RESEARCH (2008)
Human Endotoxemia as a model of systemic inflammation
A. S. Andreasen et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Wnt/β-catenin signaling controls development of the blood-brain barrier
Stefan Liebner et al.
JOURNAL OF CELL BIOLOGY (2008)
Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism
Alexander Semmler et al.
JOURNAL OF NEUROINFLAMMATION (2008)
Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: Consequences for mode of action in multiple sclerosis
Carolyn A. Foster et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
The BMP ligand Gbb gates the expression of synaptic horneostasis independent of synaptic growth control
Carleton P. Goold et al.
NEURON (2007)
Sepsis-associated delirium
Marion Ebersoldt et al.
INTENSIVE CARE MEDICINE (2007)
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
Liya Qin et al.
GLIA (2007)
Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model
Alexander Semmler et al.
EXPERIMENTAL NEUROLOGY (2007)
Tumor necrosis factor α and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier
Bjorn Bauer et al.
MOLECULAR PHARMACOLOGY (2007)
The multiple faces of caveolae
Robert G. Parton et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases
Nitai C. Hait et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)
Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: Role of intracellular calcium and nitric oxide
Dong-Mei Zheng et al.
HEPATOLOGY (2006)
Blood-brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions
Yuri Persidsky et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2006)
Distinct mechanisms of clathrin-independent endocytosis have unique sphingolipid requirements
Zhi-Jie Cheng et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Blood-brain barrier dysfunction and recovery
AG de Boer et al.
JOURNAL OF NEURAL TRANSMISSION (2006)
Oxidative variables, in the rat brain after sepsis induced by cecal ligation and perforation
T Barichello et al.
CRITICAL CARE MEDICINE (2006)
Brain endothelial hemostasis regulation by pericytes
JA Kim et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2006)
Astrocyte-endothelial interactions at the blood-brain barrier
NJ Abbott et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Critical role of actin in modulating BBB permeability
CH Lai et al.
BRAIN RESEARCH REVIEWS (2005)
Low-dose endotoxemia and human neuropsychological functions
KS Krabbe et al.
BRAIN BEHAVIOR AND IMMUNITY (2005)
Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes
JR Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The blood-brain barrier/neurovascular unit in health and disease
BT Hawkins et al.
PHARMACOLOGICAL REVIEWS (2005)
New horizons for primary intracerebral hemorrhage treatment: experience from preclinical studies
J Aronowski et al.
NEUROLOGICAL RESEARCH (2005)
Caveolae participate in tumor necrosis factor receptor 1 signaling and internalization in a human endothelial cell line
A D'Alessio et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons
IC Hellstrom et al.
HIPPOCAMPUS (2005)
Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10 -: a role for IL-1β?
AM Lynch et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury
XQ Peng et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2004)
The blood-brain barrier: an overview - Structure, regulation, and clinical implications
P Ballabh et al.
NEUROBIOLOGY OF DISEASE (2004)
Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53-and Bax-dependent pathways
HW Yung et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability
T Sanchez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation
SM Pitson et al.
EMBO JOURNAL (2003)
Role of sphingosine-1 phosphate in the enhancement of endothelial barrier integrity by platelet-released products
KL Schaphorst et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2003)
The roles of ceramide and complex sphingolipids in neuronal cell function
R Buccoliero et al.
PHARMACOLOGICAL RESEARCH (2003)
Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: modulation with anti-ICAM-1 antibodies
H Yuan et al.
BRAIN RESEARCH (2003)
S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin
Y Shikata et al.
JOURNAL OF APPLIED PHYSIOLOGY (2003)
Multifocal necrotizing leukoencephalopathy in septic shock
T Sharshar et al.
CRITICAL CARE MEDICINE (2002)
Sphingosine 1-phosphate, a key cell signaling molecule.
S Spiegel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
V Brinkmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Tight junctions of the blood-brain barrier: Development, composition and regulation
H Wolburg et al.
VASCULAR PHARMACOLOGY (2002)
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling
P Xia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Lipopolysaccharide causes deficits in spatial learning in the watermaze but not in BDNF expression in the rat dentate gyrus
KN Shaw et al.
BEHAVIOURAL BRAIN RESEARCH (2001)
Tumour necrosis factor-α causes an increase in blood-brain barrier permeability during sepsis
N Tsao et al.
JOURNAL OF MEDICAL MICROBIOLOGY (2001)
Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
JGN Garcia et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Pathophysiology of septic encephalopathy: A review
MC Papadopoulos et al.
CRITICAL CARE MEDICINE (2000)
Share Paper
