Reporting and methodological quality of meta-analyses in urological literature

Purpose. To assess the overall quality of published urological meta-analyses and identify predictive factors for high quality. Materials and Methods. We systematically searched PubMed to identify meta-analyses published from January 1st, 2011 to December 31st, 2015 in 10 predetermined major paper-based urology journals. The characteristics of the included meta-analyses were collected, and their reporting and methodological qualities were assessed by the PRISMA checklist (27 items) and AMSTAR tool (11 items), respectively. Descriptive statistics were used for individual items as a measure of overall compliance, and PRISMA and AMSTAR scores were calculated as the sum of adequately reported domains. Logistic regression was used to identify predictive factors for high qualities. Results. A total of 183 meta-analyses were included. The mean PRISMA and AMSTAR scores were 22.74 +/- 2.04 and 7.57 +/- 1.41, respectively. PRISMA item 5, protocol and registration, items 15 and 22, risk of bias across studies, items 16 and 23, additional analysis had less than 50% adherence. AMSTAR item 1, a priori'' design, item 5, list of studies and item 10, publication bias had less than 50% adherence. Logistic regression analyses showed that funding support and a priori'' design were associated with superior reporting quality, following PRISMA guideline and a priori'' design were associated with superior methodological quality. Conclusions. Reporting and methodological qualities of recently published meta-analyses in major paper-based urology journals are generally good. Further improvement could potentially be achieved by strictly adhering to PRISMA guideline and having a priori'' protocol.