Journal
NANOMATERIALS
Volume 7, Issue 12, Pages -Publisher
MDPI AG
DOI: 10.3390/nano7120411
Keywords
lanthanide; upconversion; nanoparticles; diagnostics; sensing
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Funding
- National Research Foundation of Korea (NRF) - Korea government (Ministry of Science, ICT & Future Planning) [2016R1A4A1012224]
- National Research Foundation of Korea [2016R1A4A1012224] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Lanthanide-doped nanoparticles exhibit unique optical properties, such as a long luminescence lifetime (up to several milliseconds), sharp emission peaks, and upconversion luminescence over the range of wavelengths from near-infrared to visible. Exploiting these optical properties, lanthanide-doped nanoparticles have been widely utilized for cellular and small animal imaging with the absence of background autofluorescence. In addition, these nanoparticles have advantages of high signal-to-noise ratio for highly sensitive and selective diagnostic detection. In this review, we summarize and discuss recent progress in the development of highly sensitive diagnostic methods using lanthanide-doped nanoparticles. Combined with a smartphone, portable luminescence detecting platforms could be widely applied in point-of-care tests.
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