Hybrid molecules comprising 1,2,4-triazole or diaminothiadiazole Schiff-bases and ionic liquid moieties as potent antibacterial and marine antibiofouling nominees

The buildup of marine biofouling is a serious problem due to its harmful impacts upon maritime activities and mariculture. So there is urgent call to explore novel strategy to battle this phenomenon. In pursuit of this, we have successfully prepared and characterized new thiadiazole-based bis-Schiff-bases and triazole derivatives by a combination of quaternization, heterocyclization, Schiff-base strategies. These new architectures exhibited moderate to excellent and broad-spectrum antibacterial efficacy in comparison to standard antifoulant, Diuron (R), against common panel of biofilm-inducing marine bacteria. The new compounds were blended in the matrix of inert commercial paint to formulate anticipated antibiofouling coatings. Our antibiofouling field study reveals that such materials can effectively inhibit the formation of slime films, the adhesion and colonization of diverse marine biofouling organisms such as macroalgae, tube worms, bryozoan, asidian and zooids. Further study is needed on blending these compounds which may offer promising antifouling hybrid composite and novel strategy to fight marine biofouling. (C) 2016 Elsevier Ltd. All rights reserved.