4.6 Article

Ultra-sensitive diagnosis of orthotopic patient derived hepatocellular carcinoma by Fe@graphene nanoparticles in MRI

Journal

RSC ADVANCES
Volume 6, Issue 115, Pages 113919-113923

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra23511e

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Funding

  1. National Natural Science Foundation of China [21474047]
  2. Natural Science Foundation of Jiangsu Province [BK20141225]

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We synthesized core-shell structured Fe/G-PEG NPs composed of an Fe core and a PEGylated graphene, which exhibited superior stability against oxidation, good water dispersity, low cytotoxicity and high magnetic performance. These advantages ensure them as candidates for ultra-sensitive contrast enhanced magnetic resonance imaging agents in vivo.

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