Journal
MEMBRANES
Volume 6, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/membranes6040055
Keywords
glucose biosensor; semipermeable membrane; glucose oxidase; pyrolloquinoline quinone glucose dehydrogenase; polypyrrole; poly(3,4-ethylenedioxythiophene); cellulose acetate
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Funding
- National Science Foundation, United States (Award ECCS) [1349603]
- Div Of Electrical, Commun & Cyber Sys
- Directorate For Engineering [1349603] Funding Source: National Science Foundation
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Glucose biosensors have received significant attention in recent years due to the escalating mortality rate of diabetes mellitus. Although there is currently no cure for diabetes mellitus, individuals living with diabetes can lead a normal life by maintaining tight control of their blood glucose levels using glucose biosensors (e.g., glucometers). Current research in the field is focused on the optimization and improvement in the performance of glucose biosensors by employing a variety of glucose selective enzymes, mediators and semipermeable membranes to improve the electron transfer between the active center of the enzyme and the electrode substrate. Herein, we summarize the different semipermeable membranes used in the fabrication of the glucose biosensor, that result in improved biosensor sensitivity, selectivity, dynamic range, response time and stability.
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