Journal
MEDICAL GAS RESEARCH
Volume 6, Issue 4, Pages 219-222Publisher
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/2045-9912.196904
Keywords
hydrogen-saturated water/saline; hydrogen gas; free radical scavenger; anti-inflammation; anti-apoptosis; biological effect; clinical application; hydrogen-oxygen nebulizer machine
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Molecular hydrogen (H-2) medicine research has flourished since a landmark publication in Nature Medicine that revealed the antioxidant and cytoprotective effects of hydrogen gas in a focal stroke model. Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is beyond pure hydroxyl radicals scavenging. The non-toxicity at high concentrations and rapid cellular diffusion features of molecular hydrogen ensure the feasibility and readiness of its clinical translation to human patients.
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