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Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development
Hisanobu Oda et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
RPA-like Mammalian Ctc1-Stn1-Ten1 Complex Binds to Single-Stranded DNA and Protects Telomeres Independently of the Pot1 Pathway
Yasuyuki Miyake et al.
MOLECULAR CELL (2009)
TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres
Zhong Deng et al.
MOLECULAR CELL (2009)
Conserved Telomere Maintenance Component 1 Interacts with STN1 and Maintains Chromosome Ends in Higher Eukaryotes
Yulia V. Surovtseva et al.
MOLECULAR CELL (2009)
Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair
Ivan M. Munoz et al.
MOLECULAR CELL (2009)
Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes
Ashby J. Morrison et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs
Hyeung Kim et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway
Angela Rizzo et al.
NUCLEIC ACIDS RESEARCH (2009)
Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain
Amy D. Gelinas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
How Shelterin Protects Mammalian Telomeres
Wilhelm Palm et al.
ANNUAL REVIEW OF GENETICS (2008)
Flap endonuclease 1 contributes to telomere stability
Abhishek Saharia et al.
CURRENT BIOLOGY (2008)
Endogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation
Ilja Demuth et al.
DNA REPAIR (2008)
A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse
Gunnar Schotta et al.
GENES & DEVELOPMENT (2008)
Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres
Yasutoshi Tatsumi et al.
GENES TO CELLS (2008)
The human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities
Venkateswarlu Popuri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Distinct roles of TRF1 in the regulation of telomere structure and lengthening
Keiji Okamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links
J-B Bae et al.
ONCOGENE (2008)
Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication
Arkaitz Ibarra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins
Yong Chen et al.
SCIENCE (2008)
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
Stefan Schoeftner et al.
NATURE CELL BIOLOGY (2008)
PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase
Mathieu Tardat et al.
JOURNAL OF CELL BIOLOGY (2007)
Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress
Xin Quan Ge et al.
GENES & DEVELOPMENT (2007)
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: Diverse higher order DNA and RNA targets for cancer therapeutics
Dinshaw J. Patel et al.
NUCLEIC ACIDS RESEARCH (2007)
The origin recognition complex localizes to telomere repeats and prevents telomere-circle formation
Zhong Deng et al.
CURRENT BIOLOGY (2007)
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis
Xiaolan Guo et al.
EMBO JOURNAL (2007)
Telomeric repeat-containing RNA and RNA surveillance factors at mammalian chromosome ends
Claus M. Azzalin et al.
SCIENCE (2007)
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1
Eros Lazzerini Denchi et al.
NATURE (2007)
Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome
Kakkad Regha et al.
MOLECULAR CELL (2007)
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
Kok-Lung Chan et al.
EMBO JOURNAL (2007)
Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast
Makoto Hayashi et al.
EMBO JOURNAL (2007)
The epigenetic regulation of mammalian telomeres
Maria A. Blasco
NATURE REVIEWS GENETICS (2007)
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
Ramiro E. Verdun et al.
CELL (2006)
Genome-wide characterization of fission yeast DNA replication origins
Christian Heichinger et al.
EMBO JOURNAL (2006)
Human replication protein a unfolds telomeric G-quadruplexes
Tonatiuh Romero Salas et al.
NUCLEIC ACIDS RESEARCH (2006)
The G-quadruplex ligand telomestatin inhibits POT1 binding to Telomeric sequences in vitro and induces GFP-POT1 dissociation from telomeres in human cells
Dennis Gomez et al.
CANCER RESEARCH (2006)
The Apollo 5′ exonuclease functions together with TRF2 to protect telomeres from DNA repair
Christelle Lenain et al.
CURRENT BIOLOGY (2006)
Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase
Megan van Overbeek et al.
CURRENT BIOLOGY (2006)
The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase α in the initiation of DNA replication
Kumiko Matsuno et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
ORC binding to TRF2 stimulates OriP replication
Constandache Atanasiu et al.
EMBO REPORTS (2006)
hSnm1B is a novel telomere-associated protein
Brian D. Freibaum et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Telomeres and telomerase biology in vertebrates: Progress towards a non-human model for replicative senescence and ageing
T Davis et al.
BIOGERONTOLOGY (2005)
Elevated telomere-telomere recombination in WRN-deficient, telomere dystunctional cells promotes escape from senescence and engagement of the ALT pathway
PR Laud et al.
GENES & DEVELOPMENT (2005)
POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates
PL Opresko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro
AJ Zaug et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome
MN Sangrithi et al.
CELL (2005)
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
S Gonzalo et al.
NATURE CELL BIOLOGY (2005)
Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats
R Ohki et al.
NUCLEIC ACIDS RESEARCH (2004)
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
L Crabbe et al.
SCIENCE (2004)
Regulation of murine telomere length by Rtel:: An essential gene encoding a helicase-like protein
H Ding et al.
CELL (2004)
Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation
I Demuth et al.
ONCOGENE (2004)
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2
PL Opresko et al.
MOLECULAR CELL (2004)
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
G Schotta et al.
GENES & DEVELOPMENT (2004)
The structure of telomeric DNA
S Neidle et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2003)
The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis
DJ Stavropoulos et al.
HUMAN MOLECULAR GENETICS (2002)
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases
PL Opresko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition
MD Huber et al.
NUCLEIC ACIDS RESEARCH (2002)
Replication timing of human telomeric DNA and other repetitive sequences analyzed by fluorescence in situ hybridization and flow cytometry
M Hultdin et al.
EXPERIMENTAL CELL RESEARCH (2001)
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
P Mohaghegh et al.
NUCLEIC ACIDS RESEARCH (2001)
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