Related references
Note: Only part of the references are listed.Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma
James M. Dolezal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Deubiquitinating enzyme USP22 positively regulates c-Myc stability and tumorigenic activity in mammalian and breast cancer cells
Dongyeon Kim et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2017)
A Next-Generation Sequencing Strategy for Evaluating the Most Common Genetic Abnormalities in Multiple Myeloma
Cristina Jimenez et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2017)
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
Kristen M. Turner et al.
NATURE (2017)
Genomic hallmarks of localized, non-indolent prostate cancer
Michael Fraser et al.
NATURE (2017)
The NOTCH1-MYC highway toward T-cell acute lymphoblastic leukemia
Marta Sanchez-Martin et al.
BLOOD (2017)
Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma
Lauren Fishbein et al.
CANCER CELL (2017)
Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
Xiaoyang Zhang et al.
NATURE GENETICS (2016)
Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer
Sophia Pinz et al.
BMC MOLECULAR BIOLOGY (2016)
Long-Term ERK Inhibition in KRAS-Mutant Pancreatic Cancer Is Associated with MYC Degradation and Senescence-like Growth Suppression
Tikvah K. Hayes et al.
CANCER CELL (2016)
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Hui Zhang et al.
CELL (2016)
BRAF and MEK inhibitors in pediatric glioma: new therapeutic strategies, new toxicities
Daniela Rizzo et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2016)
Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma
Huabo Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Divergent clonal selection dominates medulloblastoma at recurrence
A. Sorana Morrissy et al.
NATURE (2016)
Active medulloblastoma enhancers reveal subgroup-specific cellular origins
Charles Y. Lin et al.
NATURE (2016)
Proteogenomics connects somatic mutations to signalling in breast cancer
Philipp Mertins et al.
NATURE (2016)
Genomic analyses identify molecular subtypes of pancreatic cancer
Peter Bailey et al.
NATURE (2016)
Co-occurrence of MYC amplification and TP53 mutations in human cancer
Peter Ulz et al.
NATURE GENETICS (2016)
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma
Ximena Bonilla et al.
NATURE GENETICS (2016)
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
Himisha Beltran et al.
NATURE MEDICINE (2016)
Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors
Mark W. Richards et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype
Feimeng Zheng et al.
NATURE COMMUNICATIONS (2016)
Integrated multi-omics analysis of oligodendroglial tumours identifies three subgroups of 1p/19q co-deleted gliomas
Aurelie Kamoun et al.
NATURE COMMUNICATIONS (2016)
IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation
Yavuz Oktay et al.
SCIENTIFIC REPORTS (2016)
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
Holger Heyn et al.
GENOME BIOLOGY (2016)
Small-molecule inhibitors of the Myc oncoprotein
Steven Fletcher et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2015)
Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease
Rebecca M. Hill et al.
CANCER CELL (2015)
Integrative Clinical Genomics of Advanced Prostate Cancer
Dan Robinson et al.
CELL (2015)
The Molecular Taxonomy of Primary Prostate Cancer
Adam Abeshouse et al.
CELL (2015)
c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4
Roman Gonzalez-Prieto et al.
CELL CYCLE (2015)
Telomerase activation by genomic rearrangements in high-risk neuroblastoma
Martin Peifer et al.
NATURE (2015)
The consensus molecular subtypes of colorectal cancer
Justin Guinney et al.
NATURE MEDICINE (2015)
Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function
Sophia Pinz et al.
NUCLEIC ACIDS RESEARCH (2015)
Cancer whole-genome sequencing: present and future
H. Nakagawa et al.
ONCOGENE (2015)
The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc
Xiao-Xin Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Review The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge
Katarzyna Tomczak et al.
Wspolczesna Onkologia-Contemporary Oncology (2015)
DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer
Andrew Stone et al.
NATURE COMMUNICATIONS (2015)
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
Agnieszka K. Witkiewicz et al.
NATURE COMMUNICATIONS (2015)
Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma
Russell J. H. Ryan et al.
CANCER DISCOVERY (2015)
A common functional consequence of tumor-derived mutations within c-MYC
A. A. Chakraborty et al.
ONCOGENE (2015)
USP37 directly deubiquitinates and stabilizes c-Myc in lung cancer
J. Pan et al.
ONCOGENE (2015)
AXIN1 and AXIN2 variants in gastrointestinal cancers
Serina M. Mazzoni et al.
CANCER LETTERS (2014)
The deubiquitinase U5P28 controls intestinal homeostasis and promotes colorectal cancer
Markus E. Diefenbacher et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Inactivation of MYC reverses tumorigenesis
Y. Li et al.
JOURNAL OF INTERNAL MEDICINE (2014)
Promiscuous MYC locus rearrangements hijack enhancers but mostly super-enhancers to dysregulate MYC expression in multiple myeloma
M. Affer et al.
LEUKEMIA (2014)
Comprehensive molecular profiling of lung adenocarcinoma
Eric A. Collisson et al.
NATURE (2014)
Proteogenomic characterization of human colon and rectal cancer
Bing Zhang et al.
NATURE (2014)
PVT1 dependence in cancer with MYC copy-number increase
Yuen-Yi Tseng et al.
NATURE (2014)
A NOTCH 1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia
Daniel Herranz et al.
NATURE MEDICINE (2014)
Burkitt's lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis
V. H. Cowling et al.
ONCOGENE (2014)
SUMOylation of Myc-Family Proteins
Arianna Sabo et al.
PLOS ONE (2014)
Transcriptomic Characterization of Hepatocellular Carcinoma with CTNNB1 Mutation
Xiao Ding et al.
PLOS ONE (2014)
Identification of c-MYC SUMOylation by Mass Spectrometry
Manpreet Kalkat et al.
PLOS ONE (2014)
MAX Inactivation in Small Cell Lung Cancer Disrupts MYC-SWI/SNF Programs and Is Synthetic Lethal with BRG1
Octavio A. Romero et al.
CANCER DISCOVERY (2014)
Molecular Profiling of the Residual Disease of Triple-Negative Breast Cancers after Neoadjuvant Chemotherapy Identifies Actionable Therapeutic Targets
Justin M. Balko et al.
CANCER DISCOVERY (2014)
Enhancer variants: evaluating functions in common disease
Olivia Corradin et al.
GENOME MEDICINE (2014)
MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity
Amanda R. Wasylishen et al.
CANCER RESEARCH (2013)
Super-Enhancers in the Control of Cell Identity and Disease
Denes Hnisz et al.
CELL (2013)
The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
Bryan King et al.
CELL (2013)
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
Junwei Shi et al.
GENES & DEVELOPMENT (2013)
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma
Zhengyan Kan et al.
GENOME RESEARCH (2013)
Comprehensivemolecular characterization of clear cell renal cell carcinoma
Chad J. Creighton et al.
NATURE (2013)
The causes and consequences of genetic heterogeneity in cancer evolution
Rebecca A. Burrell et al.
NATURE (2013)
Mutational landscape and significance across 12 major cancer types
Cyriac Kandoth et al.
NATURE (2013)
Integrated molecular analysis of clear-cell renal cell carcinoma
Yusuke Sato et al.
NATURE GENETICS (2013)
The genetic landscape of high-risk neuroblastoma
Trevor J. Pugh et al.
NATURE GENETICS (2013)
Pan-cancer patterns of somatic copy number alteration
Travis I. Zack et al.
NATURE GENETICS (2013)
Emerging landscape of oncogenic signatures across human cancers
Giovanni Ciriello et al.
NATURE GENETICS (2013)
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
Jianjiong Gao et al.
SCIENCE SIGNALING (2013)
e-Blood High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations
Michael W. M. Kuehn et al.
BLOOD (2012)
Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC
Fredrik J. Swartling et al.
CANCER CELL (2012)
A Mouse Model of the Most Aggressive Subgroup of Human Medulloblastoma
Daisuke Kawauchi et al.
CANCER CELL (2012)
A Comprehensive Survey of Ras Mutations in Cancer
Ian A. Prior et al.
CANCER RESEARCH (2012)
Transcriptional Amplification in Tumor Cells with Elevated c-Myc
Charles Y. Lin et al.
CELL (2012)
Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
Marcin Imielinski et al.
CELL (2012)
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Trevor J. Pugh et al.
NATURE (2012)
Novel mutations target distinct subgroups of medulloblastoma
Giles Robinson et al.
NATURE (2012)
Dissecting the genomic complexity underlying medulloblastoma
David T. W. Jones et al.
NATURE (2012)
Recurrent R-spondin fusions in colon cancer
Somasekar Seshagiri et al.
NATURE (2012)
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
Roland Schmitz et al.
NATURE (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
Comprehensive molecular portraits of human breast tumours
Daniel C. Koboldt et al.
NATURE (2012)
Clonal selection drives genetic divergence of metastatic medulloblastoma
Xiaochong Wu et al.
NATURE (2012)
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
Jan J. Molenaar et al.
NATURE (2012)
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
Paul A. Northcott et al.
NATURE (2012)
Comprehensive genomic characterization of squamous cell lung cancers
Peter S. Hammerman et al.
NATURE (2012)
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia
Oliver Hantschel et al.
NATURE CHEMICAL BIOLOGY (2012)
The genetic landscape of mutations in Burkitt lymphoma
Cassandra Love et al.
NATURE GENETICS (2012)
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing
Julia Richter et al.
NATURE GENETICS (2012)
Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
Howard I. Scher et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Notch Signaling
Raphael Kopan
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
Ethan Cerami et al.
CANCER DISCOVERY (2012)
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Jake E. Delmore et al.
CELL (2011)
Wnt/Myc interactions in intestinal cancer: Partners in crime
Kevin Myant et al.
EXPERIMENTAL CELL RESEARCH (2011)
Medulloblastoma Comprises Four Distinct Molecular Variants
Paul A. Northcott et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma
W-J Chng et al.
LEUKEMIA (2011)
Integrated genomic analyses of ovarian carcinoma
D. Bell et al.
NATURE (2011)
Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma
Inaki Comino-Mendez et al.
NATURE GENETICS (2011)
Multiple Wnt/β-Catenin Responsive Enhancers Align with the MYC Promoter through Long-Range Chromatin Loops
Gregory S. Yochum
PLOS ONE (2011)
c-Myc Regulates Transcriptional Pause Release
Peter B. Rahl et al.
CELL (2010)
An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer
Nora F. Wasserman et al.
GENOME RESEARCH (2010)
Upregulation of c-MYC in cis through a Large Chromatin Loop Linked to a Cancer Risk-Associated Single-Nucleotide Polymorphism in Colorectal Cancer Cells
Jason B. Wright et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
The landscape of somatic copy-number alteration across human cancers
Rameen Beroukhim et al.
NATURE (2010)
International network of cancer genome projects
Thomas J. Hudson et al.
NATURE (2010)
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC
Nasim Ahmadiyeh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Overall Genomic Pattern Is a Predictor of Outcome in Neuroblastoma
Isabelle Janoueix-Lerosey et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer
Mark M. Pomerantz et al.
NATURE GENETICS (2009)
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling
Sari Tuupanen et al.
NATURE GENETICS (2009)
Meta-Analysis and Gene Set Enrichment Relative to ER Status Reveal Elevated Activity of MYC and E2F in the Basal Breast Cancer Subgroup
M. Chehani Alles et al.
PLOS ONE (2009)
A Core MYC Gene Expression Signature Is Prominent in Basal-Like Breast Cancer but Only Partially Overlaps the Core Serum Response
Sanjay Chandriani et al.
PLOS ONE (2009)
Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia
Ina Radtke et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGAP interaction
Lothar Gremer et al.
BIOLOGICAL CHEMISTRY (2008)
Distinct Thresholds Govern Myc's Biological Output In Vivo
Daniel J. Murphy et al.
CANCER CELL (2008)
Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer
Stefano Cairo et al.
CANCER CELL (2008)
Genome-wide association studies in cancer
Douglas F. Easton et al.
HUMAN MOLECULAR GENETICS (2008)
Modelling Myc inhibition as a cancer therapy
Laura Soucek et al.
NATURE (2008)
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3
Ian P. M. Tomlinson et al.
NATURE GENETICS (2008)
In vivo identification of novel STAT5 target genes
Beth Basham et al.
NUCLEIC ACIDS RESEARCH (2008)
Global Identification of Myc Target Genes Reveals Its Direct Role in Mitochondrial Biogenesis and Its E-Box Usage In Vivo
Jonghwan Kim et al.
PLOS ONE (2008)
Identification of Functional Networks of Estrogen- and c-Myc-Responsive Genes and Their Relationship to Response to Tamoxifen Therapy in Breast Cancer
Elizabeth A. Musgrove et al.
PLOS ONE (2008)
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1
Jidong Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Helical domain and kinase domain mutations in p110α of phosphatidylinositol 3-kinase induce gain of function by different mechanisms
Li Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
Frank Westermann et al.
GENOME BIOLOGY (2008)
Etiology-dependent molecular mechanisms in human hepatocarcinogenesis
Christof Schlaeger et al.
HEPATOLOGY (2008)
MYC - TIMELINE Reflecting on 25 years with MYC
Natalie Meyer et al.
NATURE REVIEWS CANCER (2008)
FBXW7/hCDC4 is a general tumor suppressor in human cancer
Shahab Akhoondi et al.
CANCER RESEARCH (2007)
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
Jennifer O'Neil et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
Benjamin J. Thompson et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
A common genetic risk factor for colorectal and prostate cancer
Christopher A. Haiman et al.
NATURE GENETICS (2007)
The ubiquitin-specific protease USP28 is required for MYC stability
Nikita Popov et al.
NATURE CELL BIOLOGY (2007)
Reversible smad-dependent signaling between tumor suppression and oncogenesis
Go Sekimoto et al.
CANCER RESEARCH (2007)
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
P. J. Roberts et al.
ONCOGENE (2007)
Multiple regions within 8q24 independently affect risk for prostate cancer
Christopher A. Haiman et al.
NATURE GENETICS (2007)
The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding
Victoria H. Cowling et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Multiple myeloma
Seema Singhal et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations?
Stefan Aretz et al.
PEDIATRIC BLOOD & CANCER (2006)
Genome-wide analysis of estrogen receptor binding sites
Jason S. Carroll et al.
NATURE GENETICS (2006)
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
Andrew P. Weng et al.
GENES & DEVELOPMENT (2006)
The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest
NG Nagl et al.
CANCER RESEARCH (2006)
Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription
F Faiola et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Six lysine residues on c-Myc are direct substrates for acetylation by p300
KL Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Prognostic and therapeutic significance of myeloma genetics and gene expression profiling
AK Stewart et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
MT Hemann et al.
NATURE (2005)
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
C James et al.
NATURE (2005)
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
E Yeh et al.
NATURE CELL BIOLOGY (2004)
Transforming growth factor β-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element
JP Frederick et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Negative control of the Myc protein by the stress-responsive kinase Pak2
ZD Huang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
M Welcker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
PI3K-Akt pathway: Its functions and alterations in human cancer
M Osaki et al.
APOPTOSIS (2004)
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size
M Welcker et al.
CURRENT BIOLOGY (2004)
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
AP Weng et al.
SCIENCE (2004)
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
M Yada et al.
EMBO JOURNAL (2004)
Phosphorylation by glycogen synthase kinase-3 controls c-Myc proteolysis and subnuclear localization
MA Gregory et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression
DYL Mao et al.
CURRENT BIOLOGY (2003)
Skp2 regulates Myc protein stability and activity
SY Kim et al.
MOLECULAR CELL (2003)
Genomic targets of the human c-Myc protein
PC Fernandez et al.
GENES & DEVELOPMENT (2003)
Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter
SR Eberhardy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Activation of phosphoinositide 3-kinase γ by Ras
S Suire et al.
CURRENT BIOLOGY (2002)
Mutations of the BRAF gene in human cancer
H Davies et al.
NATURE (2002)
c-myc is a downstream target of the Smad pathway
K Yagi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism
SR Eberhardy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome
N Miyamoto et al.
LEUKEMIA (2001)
Skp2 is oncogenic and overexpressed in human cancers
M Gstaiger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b
J Seoane et al.
NATURE CELL BIOLOGY (2001)
Defective repression of c-myc in breast cancer cells:: A loss at the core of the transforming growth factor β growth arrest program
CR Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
R Sears et al.
GENES & DEVELOPMENT (2000)
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling
WG Liu et al.
NATURE GENETICS (2000)
Constitutive activation of STAT5 by a point mutation in the SH2 domain
K Ariyoshi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The c-myc transactivation domain is a direct modulator of apoptotic versus proliferative signals
DW Chang et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5
JD Lord et al.
JOURNAL OF IMMUNOLOGY (2000)