Related references
Note: Only part of the references are listed.Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket
Bingfa Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity
Robert K. Y. Cheng et al.
STRUCTURE (2017)
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
Tobias Weinert et al.
NATURE COMMUNICATIONS (2017)
Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation
Jose M. Martin-Garcia et al.
IUCRJ (2017)
Fast iodide-SAD phasing for high-throughput membrane protein structure determination
Igor Melnikov et al.
SCIENCE ADVANCES (2017)
Mini-G proteins: Novel tools for studying GPCRs in their active conformation
Rony Nehme et al.
PLOS ONE (2017)
Active state structures of G protein-coupled receptors highlight the similarities and differences in the G protein and arrestin coupling interfaces
Byron Carpenter et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)
Activation processes in ligand-activated G protein-coupled receptors: A case study of the adenosine A2A receptor
R. Scott Prosser et al.
BIOESSAYS (2017)
Expression, Purification and Crystallisation of the Adenosine A2A Receptor Bound to an Engineered Mini G Protein
Byron Carpenter et al.
BIO-PROTOCOL (2017)
Expression and Purification of Mini G Proteins from Escherichia coli
Byron Carpenter et al.
BIO-PROTOCOL (2017)
Structure of the Adenosine A1 Receptor Reveals the Basis for Subtype Selectivity
Alisa Glukhova et al.
CELL (2017)
Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength
Elena Segala et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Structure of the adenosine A2A receptor bound to an engineered G protein
Byron Carpenter et al.
NATURE (2016)
Activation of the A2A adenosine G-protein-coupled receptor by conformational selection
Libin Ye et al.
NATURE (2016)
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
A. J. Venkatakrishnan et al.
NATURE (2016)
A mutagenesis and screening strategy to generate optimally thermostabilized membrane proteins for structural studies
Francesca Magnani et al.
NATURE PROTOCOLS (2016)
Engineering a minimal G protein to facilitate crystallisation of G protein-coupled receptors in their active conformation
Byron Carpenter et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2016)
Native phasing of x-ray free-electron laser data for a G protein-coupled receptor
Alexander Batyuk et al.
SCIENCE ADVANCES (2016)
Molecular Basis of Ligand Dissociation from the Adenosine A2A Receptor
Dong Guo et al.
MOLECULAR PHARMACOLOGY (2016)
Structure-Activity Analysis of Biased Agonism at the Human Adenosine A3 Receptor
Jo-Anne Baltos et al.
MOLECULAR PHARMACOLOGY (2016)
Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling
Aashish Manglik et al.
CELL (2015)
From G Protein-coupled Receptor Structure Resolution to Rational Drug Design
Ali Jazayeri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Novel Allosteric Modulators of G Protein-coupled Receptors
Patrick R. Gentry et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Universal allosteric mechanism for Gα activation by GPCRs
Tilman Flock et al.
NATURE (2015)
A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes
Martin Caffrey
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2015)
Molecular Determinants of CGS21680 Binding to the Human Adenosine A2A Receptor
Guillaume Lebon et al.
MOLECULAR PHARMACOLOGY (2015)
Probing biased/partial agonism at the G protein-coupled A2B adenosine receptor
Zhan-Guo Gao et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Adenosine-a physiological or pathophysiological agent?
Bertil B. Fredholm
JOURNAL OF MOLECULAR MEDICINE-JMM (2014)
Allosteric sodium in class A GPCR signaling
Vsevolod Katritch et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Molecular signatures of G-protein-coupled receptors
A. J. Venkatakrishnan et al.
NATURE (2013)
OPINION Signalling bias in new drug discovery: detection, quantification and therapeutic impact
Terry Kenakin et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Adenosine receptors as drug targets - what are the challenges?
Jiang-Fan Chen et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
The Role of a Sodium Ion Binding Site in the Allosteric Modulation of the A2A Adenosine G Protein-Coupled Receptor
Hugo Gutierrez-de-Teran et al.
STRUCTURE (2013)
Agonist-bound structures of G protein-coupled receptors
Guillaume Lebon et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2012)
Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design
Miles Congreve et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Structure of the agonist-bound neurotensin receptor
Jim F. White et al.
NATURE (2012)
G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
Tomoya Hino et al.
NATURE (2012)
Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
Wei Liu et al.
SCIENCE (2012)
Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors
Eugene Chun et al.
STRUCTURE (2012)
Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol
Tony Warne et al.
STRUCTURE (2012)
Recent developments in adenosine receptor ligands and their potential as novel drugs
Christa E. Mueller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)
Nanobody stabilization of G protein-coupled receptor conformational states
Jan Steyaert et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2011)
Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A2A Receptor
Guillaume Lebon et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
Guillaume Lebon et al.
NATURE (2011)
The structural basis for agonist and partial agonist action on a β1-adrenergic receptor
Tony Warne et al.
NATURE (2011)
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
Soren G. F. Rasmussen et al.
NATURE (2011)
Structure and function of an irreversible agonist-β2 adrenoceptor complex
Daniel M. Rosenbaum et al.
NATURE (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors-An Update
Bertil B. Fredholm et al.
PHARMACOLOGICAL REVIEWS (2011)
Structural flexibility of the Gas α-helical domain in the β2-adrenoceptor Gs complex
Gerwin H. Westfield et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Functional selectivity of adenosine receptor ligands
Dennis Verzijl et al.
PURINERGIC SIGNALLING (2011)
Structure of an Agonist-Bound Human A2A Adenosine Receptor
Fei Xu et al.
SCIENCE (2011)
Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine
Andrew S. Dore et al.
STRUCTURE (2011)
Engineering G protein-coupled receptors to facilitate their structure determination
Christopher G. Tate et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)
Thermostabilization of the Neurotensin Receptor NTS1
Yoko Shibata et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The structure and function of G-protein-coupled receptors
Daniel M. Rosenbaum et al.
NATURE (2009)
Protein crystallography with a micrometre-sized synchrotron-radiation beam
Rouslan Moukhametzianov et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2008)
Structure of a β1-adrenergic G-protein-coupled receptor
Tony Warne et al.
NATURE (2008)
Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor
Francesca Magnani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Conformational thermostabilization of the β1-adrenergic receptor in a detergent-resistant form
Maria J. Serrano-Vega et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Adenosine A2A receptors in Parkinson's disease treatment
Marek Cieslak et al.
PURINERGIC SIGNALLING (2008)
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
Veli-Pekka Jaakola et al.
SCIENCE (2008)
High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor
Vadim Cherezov et al.
SCIENCE (2007)
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
Daniel M. Rosenbaum et al.
SCIENCE (2007)
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Soren G. F. Rasmussen et al.
NATURE (2007)
Conformational complexity of G-protein-coupled receptors
Brian K. Kobilka et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
Purinergic signalling
G Burnstock
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Adenosine receptors as therapeutic targets
KA Jacobson et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Human A2A adenosine receptors:: High-affinity agonist binding to receptor-G protein complexes containing Gβ4
LJ Murphree et al.
MOLECULAR PHARMACOLOGY (2002)