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Ceramide stabilizes β-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid β-peptide biogenesis (Withdrawn Publication. See vol. 298, 2022) (Withdrawn Publication. See vol. 298, 2022)
L Puglielli et al.
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WT Kimberly et al.
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Reconstitution of γ-secretase activity
D Edbauer et al.
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Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study
AM Tully et al.
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XL Han et al.
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The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted
B Grziwa et al.
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Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
R Ehehalt et al.
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MJ Engelhart et al.
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R Styger et al.
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Fish, meat, and risk of dementia:: cohort study
P Barberger-Gateau et al.
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Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid
SS Fam et al.
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Apolipoprotein E ε4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease
M Kivipelto et al.
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Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis
XL Han et al.
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J Hardy et al.
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Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer's disease model rats
M Hashimoto et al.
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Ceramide-induced cell death in primary neuronal cultures: Upregulation of ceramide levels during neuronal apoptosis
RE Toman et al.
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Cholesterol depletion induces large scale domain segregation in living cell membranes
MM Hao et al.
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A cholesterol-lowering drug reduces β-amyloid pathology in a transgenic mouse model of Alzheimer's disease
LM Refolo et al.
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MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease
BC Dickerson et al.
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Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts
DR Riddell et al.
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A transcriptively active complex of APP with Fe65 and histone acetyltransferase Tip60
XW Cao et al.
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Brain membrane phospholipid alterations in Alzheimer's disease
JW Pettegrew et al.
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Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo
K Fassbender et al.
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Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
E Kojro et al.
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Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry
XL Han et al.
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Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment
JA Conquer et al.
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Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors
B Wolozin et al.
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CELL (2000)
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