Journal
MEDICAL MYCOLOGY CASE REPORTS
Volume 14, Issue -, Pages 33-37Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.mmcr.2016.11.008
Keywords
CNS Aspergillosis; Mycobacterium tuberculosis; Spinal Aspergillosis; CNS infections in immunocompromised
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35 yr old steroid dependent lady with Pulmonary TB underwent debridement of epidural abscess & posterior stabilization for paraparesis. With histopathology and cultures showing Aspergillus fumigatus, voricanozole was started. By the fourth week, she developed persistent fever, and altered mental status. Brain MRI and CSF study including multiplex PCR evaluation confirmed cerebral aspergillosis. Voricanozole was changed to intravenous lipid complex Amphotericin B to achieve sustained clinical and radiological response after six months of therapy.
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