Selective Electrochemical Detection of Dopamine on Polyoxometalate-Based Metal-Organic Framework and Its Composite with Reduced Graphene Oxide

The interfacing of polyoxometalates and reduced graphene oxide (rGO) can be considered to be an effective way to generate hybrid structures which colligates the advantages of both components. Here, a hybrid material (polyoxometalate-based metal-organic framework (POMOF)/rGO) integrating POMOF and rGO is obtained via a simple one-pot approach. The as-prepared materials are used as electrochemical active materials to detect dopamine for the first time. It is shown that the hybridization results in a superior catalytic activity for oxidation of dopamine owing to the synergistic effect between POMOF and rGO, as well as favorable interaction of DA with CC network of the composite. The promoted electron transfer, as well as abundant active sites, open channels, and aromatic planes in the hybrid material produce a wider linear detection range of 1 x 10(-6) to 2 x 10(-4) M with the lower detection limit of 80.4 x 10(-9)M (S/N = 3). Moreover, the developed biosensor also exhibits favorable selectivity, reproducibility, and stability. As a non-noble metal catalyst constructing from function and structure-matched building blocks, the prepared POMOF/rGO hybrid material demonstrates its highly promising properties for dopamine detection and the result should promote the further development of POMOF-based sensors.