Journal
TISSUE ENGINEERING AND REGENERATIVE MEDICINE
Volume 14, Issue 1, Pages 1-14Publisher
KOREAN TISSUE ENGINEERING REGENERATIVE MEDICINE SOC
DOI: 10.1007/s13770-016-0001-6
Keywords
Bone; Bone tissue engineering; Scaffolds; Growth factors; Regenerative medicine
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Funding
- University Grant Commission (UGC), Government of India, New Delhi
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Bone provides mechanical support, and flexibility to the body as a structural frame work along with mineral storage, homeostasis, and blood pH regulation. The repair and/or replacement of injured or defective bone with healthy bone or bone substitute is a critical problem in orthopedic treatment. Recent advances in tissue engineering have shown promising results in developing bone material capable of substituting the conventional autogenic or allogenic bone transplants. In the present review, we have discussed natural and synthetic scaffold materials such as metal and metal alloys, ceramics, polymers, etc. which are widely being used along with their cellular counterparts such as stem cells in bone tissue engineering with their pros and cons.
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