4.6 Article

Optical Flow Cell for Measuring Size, Velocity and Composition of Flowing Droplets

Journal

MICROMACHINES
Volume 8, Issue 2, Pages -

Publisher

MDPI
DOI: 10.3390/mi8020058

Keywords

droplet microfluidics; absorbance; real-time monitoring; velocity measurement; enzymatic assays; optical detections

Funding

  1. Engineering and Physical Sciences Research Council UK [EP/M012425/1]
  2. Natural Environment Research Council UK [NE/P004016/1]
  3. EPSRC [EP/M012425/1] Funding Source: UKRI
  4. NERC [NE/P004016/1] Funding Source: UKRI
  5. Engineering and Physical Sciences Research Council [EP/M012425/1] Funding Source: researchfish
  6. Natural Environment Research Council [NE/P004016/1] Funding Source: researchfish

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Here an optical flow cell with two light paths is reported that can accurately quantify the size and velocity of droplets flowing through a microchannel. The flow cell can measure the time taken for droplets to pass between and through two conjoined light paths, and thereby is capable of measuring the velocities (0.2-5.45 mm/s) and sizes of droplets (length > 0.8 mm). The composition of the droplet can also be accurately quantified via optical absorption measurements. The device has a small footprint and uses low-powered, low-cost components, which make it ideally suited for use in field-deployable and portable analytical devices.

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