Journal
TRANSCRIPTION-AUSTIN
Volume 7, Issue 1, Pages 21-25Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/21541264.2015.1127315
Keywords
Bub1; centromere; centromeric cohesion; kinetochore; mitosis; RNA polymerase II; Sgo1; transcription
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The major role of RNA polymerase II (RNAP II) is to generate mRNAs. I recently uncovered a novel function of RNAP II in chromosome segregation in mitosis, installing the cohesin protector, Shugoshin, at centromeres. Here I will discuss the current understanding of RNAP II-dependent centromeric transcription in mitosis.
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