Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 5, Issue 11, Pages 2068-2073Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6tb02826h
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Funding
- National Natural Science Foundation of China [81573366, 81473144, 8127342]
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The high aqueous instability of amorphous calcium carbonate (ACC), which will lead to a burst release of its payload, has generally been recognized as the major obstacle for its further application in nanomedicine. Herein, a locking/unlocking strategy was applied to employ the instability of ACC to realize burst drug release within cancer cells.
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