Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 5, Issue 7, Pages 1518-1524Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6tb03317b
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Funding
- National Natural Science Foundation of China [51473123, 21476176]
- Major State Research and Development Program of China [2016YFA0100800]
- Open Funds of the State Key Laboratory of Rare Earth Resource Utilization [RERU2015019]
- National Key Technology R&D Program of China [2015BAD16B01]
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Nanozymes merge nanotechnology with biology and provide a lower cost and higher stability options, compared to that of natural enzymes. However, nanozyme catalyzed polymerization under physiological conditions is still a big challenge due to heavy oxygen inhibition. In this study, the simple glucose oxidase system can effectively adjust oxygen concentration and generate hydrogen peroxide, which assists in the realization of nanozyme-catalyzed polymerization. The nanozyme based hydrogel is printable due to its mild preparation with gradually increased viscosity. The antibacterial performance is ascribed to the in situ generated hydroxyl radical via the reaction of the bound nanozyme and glucose.
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