4.6 Article

Pristine carbon nanotube scaffolds for the growth of chondrocytes

Journal

JOURNAL OF MATERIALS CHEMISTRY B
Volume 5, Issue 41, Pages 8178-8182

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7tb02065a

Keywords

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Funding

  1. Surrey Impact Acceleration Awards (IAA) [2015/KN9149C, 2015/K031562/1 + G060878]
  2. EPSRC [EP/K031562]
  3. Ministry of Education and Science of Russian Federation [14.Y26.31.0010]
  4. Engineering and Physical Sciences Research Council [EP/K031562/1] Funding Source: researchfish
  5. EPSRC [EP/K031562/1] Funding Source: UKRI

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The effective growth of chondrocytes and the formation of cartilage is demonstrated on scaffolds of aligned carbon nanotubes; as two dimensional sheets and on three dimensional textiles. Raman spectroscopy is used to confirm the presence of chondroitin sulfate, which is critical in light of the unreliability of traditional dye based assays for carbon nanomaterial substrates. The textile exhibits a very high affinity for chondrocyte growth and could present a route to implantable, flexible cartilage scaffolds with tuneable mechanical properties.

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