Journal
JOURNAL OF MATERIALS CHEMISTRY B
Volume 5, Issue 21, Pages 3810-3815Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7tb00543a
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Funding
- National Natural Science Foundation of China [21273032, 81671712]
- Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning
- Science and Technology Commission of Shanghai Municipality [15520711400]
- Fundamental Research Funds for the Central Universities
- Shanghai Sailing Program [16YF1409300]
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Multifunctional Tc-99m-labeled dendrimer-entrapped gold nano-particles (Tc-99m-Au DENPs) were designed and synthesized. Our results show that the type of surface groups (acetyl or hydroxyl) significantly impact the biodistribution profile of the Tc-99m-Au DENPs, thereby allowing for preferential SPECT/CT imaging of different organs.
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