4.3 Article

Management of Trauma-Induced Coagulopathy with Thrombelastography

Journal

CRITICAL CARE CLINICS
Volume 33, Issue 1, Pages 119-+

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccc.2016.09.002

Keywords

Coagulopathy; Resuscitation; Thrombelastography; TEG; Fibrinolysis; Transfusion

Funding

  1. Haemonetics Inc
  2. TEM International GmbH
  3. National Institute of General Medical Sciences [P50 GM049222, T32 GM008315-21]
  4. National Heart, Lung, and Blood Institute [UM1 HL120877]
  5. Department of Defense [W81XWH 12-2-0028]

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Viscoelastic assays, such as thrombelastography (TEG) and rotational thrombelastometry (ROTEM), have emerged as point-of-care tools that can guide the hemostatic resuscitation of bleeding injured patients. This article describes the role of TEG in contemporary trauma care by explaining this assay's methodology, clinical applications, and result interpretation through description of supporting studies to provide the reader with an evidence-based user's guide. Although TEG and ROTEM are assays based on the same viscoelastic principle, this article is focused on data supporting the use of TEG in trauma, because it is available in trauma centers in North America; ROTEM is mostly available in Europe.

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