Journal
BIOSENSORS & BIOELECTRONICS
Volume 87, Issue -, Pages 918-930Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2016.09.061
Keywords
Biosensor; Cancer biomarker; Functional nanomaterials; Point-of-care devices; Microfluidics
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Funding
- Russian Foundation for Basic Research [16-34-60100, 16-06-00439]
- state budget allocated to the fundamental research Russian Academy of Sciences Project [01201351504]
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The present review critically discusses the latest developments in the field of smart diagnostic systems for cancer biomarkers. A wide coverage of recent biosensing approaches involving aptamers, enzymes, DNA probes, fluorescent probes, interacting proteins and antibodies in vicinity to transducers such as electrochemical, optical and piezoelectric is presented. Recent advanced developments in biosensing approaches for cancer biomarker owes much credit to functionalized nanomaterials due to their unique opto-electronic properties and enhanced surface to volume ratio. Biosensing methods for a plenty of cancer biomarkers has been summarized emphasizing the key principles involved.
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