4.7 Article

A peptide functionalized nanomotor as an efficient cell penetrating tool

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 6, Pages 1088-1091

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc09169e

Keywords

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Funding

  1. European Research Council under the European Union [(FP7/2007-20012)/ERC-StG 307679]
  2. Ministry of Education, Culture and Science [024.001.035]
  3. China Scholarship Council

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A nanomotor based strategy for fast cellular entry and cargo delivery is presented. The concept focuses on integrating tat peptide, a basic domain of HIV-1 tat protein, with state of the art nanomotors which possess attractive autonomous properties, facilitating cellular penetration and uptake. The rapid cellular internalization process leads to higher delivery efficiency.

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