Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 162, Issue 4, Pages 421-424Publisher
SPRINGER
DOI: 10.1007/s10517-017-3630-4
Keywords
cystatin C; coronary heart disease; biochemical markers; clinical study
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The role of cystatin C, an inhibitor of cysteine proteases, as an alternative and potent predictor of acute cardiovascular events in coronary heart disease (CHD) patients was examined and compared to that of other markers of cardiorenal abnormalities. The patients with CHD demonstrated elevated serum cystatin C, especially in cases with serious risk of cardiovascular complications. In comparison with other indicators of cardiorenal dysfunction, cystatin C can be viewed as an alternative predictor of cardiovascular complications, although its sensitivity is inferior to that of high-sensitivity C-reactive protein and natriuretic peptide.
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