Journal
JOURNAL OF HEPATOCELLULAR CARCINOMA
Volume 4, Issue -, Pages -Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/JHC.S122807
Keywords
hepatocellular carcinoma; programmed death ligand 1; hepatic resection; prognoses
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Funding
- National Natural Science Foundation of the People's Republic of China [81560460, 81060173]
- Guangxi University of Science and Technology Research Projects [KY2015LX056]
- Ministry of Health of Guangxi Province [Z2015621, Z2015601, GZZC15-34]
- Innovation Project of Guangxi Graduate Education [YCBZ2015030]
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Immunotherapy targeting programmed death receptor 1 and programmed death ligand 1 (PD-L1) has shown impressive antitumor efficacy in several solid cancers, including advanced hepatocellular carcinoma (HCC). Since response rates of various cancers to such immunotherapy appear to correlate with PD-L1 expression levels, several studies have examined whether PD-L1 expression correlates with HCC pathology and patient prognosis. In this paper, we analyzed the strength and limitations of a recent meta-analysis of associations of PD-L1 with HCC characteristics and patient prognosis.
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