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Vibrio vulnificus:An Environmental and Clinical Burden

Journal

FRONTIERS IN MICROBIOLOGY
Volume 8, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2017.00997

Keywords

Vibrio vulnificus; prevalence; pathogenesis; treatment; prevention

Categories

Funding

  1. PVC Award Grant [PVC-ECR-2016]
  2. MOSTI ScienceFund Grant [06-02-10-SF0300]
  3. External Industry Grants (Biotek Abadi) [GBA-808138, GBA-808813]
  4. University of Malaya for High Impact Research Grant (UM-MOHE HIR Nature Microbiome Grant) [H-50001-A000027, A000001-50001]

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Vibrio vulnificus is a Gram negative, rod shaped bacterium that belongs to the family Vibrionaceae. It is a deadly, opportunistic human pathogen which is responsible for the majority of seafood-associated deaths worldwide. V. vulnificus infection can be fatal as it may cause severe wound infections potentially requiring amputation or lead to sepsis in susceptible individuals. Treatment is increasingly challenging as V. vulnificus has begun to develop resistance against certain antibiotics due to their indiscriminate use. This article aims to provide insight into the antibiotic resistance of V. vulnificus in different parts of the world as well as an overall review of its clinical manifestations, treatment, and prevention. Understanding the organism's antibiotic resistance profile is vital in order to select appropriate treatment and initiate appropriate prevention measures to treat and control V. vulnificus infections, which should eventually help lower the mortality rate associated with this pathogen worldwide.

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