4.7 Article

Copper-mediated oxysulfonylation of alkenyl oximes with sodium sulfinates: a facile synthesis of isoxazolines featuring a sulfone substituent

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 12, Pages 2056-2059

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc00090a

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Funding

  1. Hebei Province Science Foundation for Key Program [B2016201031]

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A novel and efficient Cu(OAc)(2)-mediated oxysulfonylation of alkenyl oximes with sodium sulfonates was developed. The reactions are easy to conduct, occur under mild conditions, and form a broad range of sulfone-substituted isoxazolines in good yields.

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