Journal
FRONTIERS IN MICROBIOLOGY
Volume 8, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fmicb.2017.00055
Keywords
xMAP; magnetic microspheres; multiplex detection; nucleic acid detection; immunoassay; pathogen identification; diagnostics
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Funding
- Ministry of Education, Youth and Sports of the Czech Republic [LO1218]
- Ministry of Agriculture of the Czech Republic [RO0516]
- Ministry of the Interior of the Czech Republic [VI20152020044]
- Masaryk University [MUNI/A/1325/2015]
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xMAP technology is applicable for high-throughput, multiplex and simultaneous detection of different analytes within a single complex sample. xMAP multiplex assays are currently available in various nucleic acid and immunoassay formats, enabling simultaneous detection and typing of pathogenic viruses, bacteria, parasites and fungi and also antigen or antibody interception. As an open architecture platform, the xMAP technology is beneficial to end users and therefore it is used in various pharmaceutical, clinical and research laboratories. The main aim of this review is to summarize the latest findings and applications in the field of pathogen detection using microsphere-based multiplex assays.
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