Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 56, Issue 9, Pages 2408-2412Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201612559
Keywords
annulations; cyclopentadienyl ligands; reaction mechanisms; rhodium catalysis
Categories
Funding
- Institute for Basic Science [IBS-R010-D1]
Ask authors/readers for more resources
A change in reaction pathway was achieved for the first time by tuning the cyclopentadienyl (Cp) ligand used for the rhodium-catalyzed cyclization of benzamides with conjugated enynones. Depending on the Cp ligand, the reaction pathway switched between [4+2] and [4+1] annulation. Electronic effects turned out to be crucial for the product distribution. The dichotomy was attributed to the alteration of the Lewis acidity of the resultant Cp-bound rhodium species.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available