Journal
CANCER LETTERS
Volume 386, Issue -, Pages 123-130Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.canlet.2016.10.032
Keywords
Nanoparticles; Gastric cancer; Theranostics; Diagnosis
Categories
Funding
- National Natural Science Foundation of China [81472216, 81672398, 81672367]
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Gastric cancer is the fourth most common cancer and the second leading cause of cancer related death worldwide. For the diagnosis of gastric cancer, apart from regular systemic imaging, the locoregional imaging is also of great importance. Moreover, there are still other ways for the detecting of gastric cancer, including the early detection of gastric cancer by endoscopy, the detection of gastric-cancer related biomarkers and the detection of circulating tumor cells (CTCs) of gastric cancer. However, conventional diagnostic methods are usually lack of specificity and sensitivity. Nanoparticles provide many benefits in the diagnosis of gastric cancer. Besides, nanoparticles are capable of integrating the functions of diagnosis and treatment together (theranostics). In this paper, we reviewed the applications of nanoparticles in diagnosis and theranostics of gastric cancer in the above mentioned aspects. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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