Journal
ELIFE
Volume 6, Issue -, Pages -Publisher
ELIFE SCIENCES PUBLICATIONS LTD
DOI: 10.7554/eLife.20156
Keywords
-
Categories
Funding
- European Molecular Biology Organization [ALTF 568-2008]
- Human Frontier Science Program [LT000563/2010]
- Biotechnology and Biological Sciences Research Council [BB/J004588/1]
- BBSRC [BBS/E/J/000CA517, BB/L008920/1, BBS/E/J/000PR9789, BBS/E/J/000PR9787, BBS/E/J/000PR9773, BB/M023117/1] Funding Source: UKRI
Ask authors/readers for more resources
Out-of-plane tissue deformations are key morphogenetic events during plant and animal development that generate 3D shapes, such as flowers or limbs. However, the mechanisms by which spatiotemporal patterns of gene expression modify cellular behaviours to generate such deformations remain to be established. We use the Snapdragon flower as a model system to address this problem. Combining cellular analysis with tissue-level modelling, we show that an orthogonal pattern of growth orientations plays a key role in generating out-of-plane deformations. This growth pattern is most likely oriented by a polarity field, highlighted by PIN1 protein localisation, and is modulated by dorsoventral gene activity. The orthogonal growth pattern interacts with other patterns of differential growth to create tissue conflicts that shape the flower. Similar shape changes can be generated by contraction as well as growth, suggesting tissue conflict resolution provides a flexible morphogenetic mechanism for generating shape diversity in plants and animals.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available