4.2 Article

Secondary Metabolites Produced by the Deep-Sea-Derived Fungus Engyodontium album

Journal

CHEMISTRY OF NATURAL COMPOUNDS
Volume 53, Issue 2, Pages 224-226

Publisher

SPRINGER
DOI: 10.1007/s10600-017-1957-8

Keywords

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Funding

  1. Scientific Research Foundation of the Third Institute of Oceanography, SOA [2014007]
  2. International Science & Technology Cooperation Program of China [2015DFA20500]
  3. Special Financial Fund of Innovative Development of Marine Economic Demonstration Project [GD2012-D01-001]
  4. China Ocean Mineral Resources RD Association [DY125-15-T-03, DY-125-15-T-08]
  5. Marine Public Welfare Project [201005022]

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Chemical investigation of the EtOH extract of a rice-fermented deep-sea-derived fungal strain, Engyodontium album, led to the isolation of a new benzoic acid derivative, named engyodontiumin A (1), together with four known compounds, 3,4-dihydroxybenzoic acid (2), 3-(2,4-dihydroxyphenyl) propionic acid (3), 3,4-dimethoxybenzoic acid (4), and trans-4-hydroxycinnamic acid (5). This strain was isolated from a marine sediment sample collected in the Atlantic Ocean (24A degrees 23' W, 0A degrees 8'N, 3542 m depth). Their structures were elucidated by spectroscopic analyses, including H-1 NMR, C-13 NMR, 2D NMR (HSQC, HMBC, COSY), and HR-ESI-MS.

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